Small plaque psoriasis re-visited: A type of psoriasis mediated by a type-I interferon pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental dermatology"
DOI: 10.1111/exd.14513
Abstract: TNFα-inhibitor-induced psoriasis is mediated by the type-I interferon pathway, of which IFNα, LL37 and IL-36γ are major players. A subset of patients treated with TNFα inhibitors develop small plaque psoriatic lesions. Small plaque psoriasis is… read more here.
Keywords: plaque psoriasis; psoriasis; type interferon; small plaque ... See more keywords
H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abf8627
Abstract: Activation of interferon genes constitutes an important anticancer pathway able to restrict proliferation of cancer cells. Here, we demonstrate that the H3K9me3 histone methyltransferase (HMT) suppressor of variegation 3–9 homolog 1 (SUV39H1) is required for… read more here.
Keywords: cells activation; activation interferon; interferon pathway; pathway ... See more keywords