Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
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DOI: 10.1016/j.celrep.2017.04.031
Abstract: SUMMARY PD-L1 and PD-L2 are ligands for the PD-1 immune inhibiting checkpoint that can be induced in tumors by interferon exposure, leading to immune evasion. This process is important for immunotherapy based on PD-1 blockade.… read more here.
Keywords: signaling pathways; pathways regulating; interferon; expression ... See more keywords
A pivotal role for Interferon-α receptor-1 in neuronal injury induced by HIV-1
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01894-2
Abstract: Background HIV-1 infection remains a major public health concern despite effective combination antiretroviral therapy (cART). The virus enters the central nervous system (CNS) early in infection and continues to cause HIV-associated neurocognitive disorders (HAND). The… read more here.
Keywords: hiv; neuronal injury; role; injury ... See more keywords