Association of polymorphisms in the HBG1‐HBD intergenic region with HbF levels
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23243
Abstract: Increased levels of fetal hemoglobin (HbF) can improve the clinical course of the patients with sickle cell anemia (SCA) or β‐thalassemia. The HBG1‐HBD intergenic region plays an important role in this process. However, very few… read more here.
Keywords: hbf; association polymorphisms; intergenic region; hbg1 hbd ... See more keywords
An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28799-8
Abstract: The Endoplasmatic Reticulum Aminopeptidases ERAP1 and ERAP2 are implicated in a variety of immune and non-immune functions. Most studies however have focused on their role in shaping the HLA class I peptidome by trimming peptides… read more here.
Keywords: erap2; erap1 erap2; intergenic region; expression ... See more keywords
A Novel LOC101927967 Intergenic Region ALK Fusion Identified by NGS and Validated by IHC and FISH in a Patient with Early Stage Adenocarcinoma of Lung
Sign Up to like & getrecommendations! Published in 2022 at "OncoTargets and therapy"
DOI: 10.2147/ott.s347200
Abstract: Abstract Anaplastic lymphoma kinase (ALK) gene rearrangement is an essential driver mutation identified in approximately 5% of non-small cell lung cancers (NSCLCs). The results of clinical trials have demonstrated the impressive efficacy of ALK tyrosine… read more here.
Keywords: lung; alk; fusion; intergenic region ... See more keywords