Hypofractionated versus standard chemoradiotherapy in the definitive treatment of uterine cervix cancer: interim results of a randomized controlled clinical trial
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-023-05563-8
Abstract: Purpose Concurrent chemoradiation has been the mainstay of treatment for cervix cancer. We aimed to evaluate the non-inferiority of hypofractionated chemoradiation. Methods This study was designed as a phase 2, 1:1 randomized, investigator-blinded, controlled, non-inferiority… read more here.
Keywords: cancer; interim results; chemoradiation; trial ... See more keywords
A Post-Marketing Surveillance Study of Nusinersen for Spinal Muscular Atrophy in Routine Medical Practice in China: Interim Results
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DOI: 10.1007/s12325-024-02852-7
Abstract: Spinal muscular atrophy (SMA) is a rare, autosomal recessive, neuromuscular disease that leads to progressive muscular weakness and atrophy. Nusinersen, an antisense oligonucleotide, was approved for SMA in China in February 2019. We report interim… read more here.
Keywords: spinal muscular; interim results; muscular atrophy; post marketing ... See more keywords
P2.04-26 Interim Results from a Phase I/II Trial of Nivolumab in Combination with CIMAvax-EGF as Second-Line Therapy in Advanced NSCLC
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.08.1250
Abstract: since we will be able to compare our results with the once published previously. Method: We have reviewed 129 patients with NSCLC, advanced or recurrent stages, treated with nivolCutumab either in second and subsequent lines… read more here.
Keywords: response; results phase; treatment; interim results ... See more keywords
Short-Term Interim Results of Clinical Outcomes and Complications After Implantation of Boston Keratoprosthesis in Japanese Patients.
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DOI: 10.1097/ico.0000000000002608
Abstract: transport cartridge. These results are in concordance with the findings of Catala et al1 who performed the transport at ambient temperature. Further examinations on different media and the influence on the metabolism of the cells,… read more here.
Keywords: results clinical; interim results; term; clinical outcomes ... See more keywords
S140 Interim results from a prospective study of tablet and web- based audiometry to detect ototoxicity in adults with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.146
Abstract: Introduction Individuals with Cystic Fibrosis (CF) often receive frequent, prolonged anti-infective therapy including aminoglycosides which result in ototoxicity. There are, however, no current national or international screening recommendations. Although high-frequency audiometry has increased sensitivity for… read more here.
Keywords: ipad; hearing loss; ototoxicity; interim results ... See more keywords
Abstract P3-01-18: Clinical validation of image-based AI predictive biomarkers for precision neoadjuvant triple-negative breast cancer treatment (PEAR-TNBC): Interim results from Cohort A
Sign Up to like & getrecommendations! Published in 2025 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.sabcs24-p3-01-18
Abstract: Background: Pathological complete response (pCR) to neoadjuvant therapy strongly predicts the risk of recurrence and death in triple-negative breast cancer (TNBC). There are multiple neoadjuvant regimens available for TNBC but no biomarkers to match patients… read more here.
Keywords: cancer; treatment; breast cancer; interim results ... See more keywords
First interim results of the Radium-223 (Ra-223) reassure observational study in metastatic castration-resistant prostate cancer (mCRPC): Safety and baseline (BL) characteristics of U.S. patients (Pts) by prior/concomitant treatment (Tx).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.233
Abstract: 233Background: Ra-223, a targeted alpha therapy, extended survival and had a favorable safety profile at 3 years’ follow up in pts with mCRPC in the pivotal phase 3 ALSYMPCA trial. The maturing global, prospective, single-arm,… read more here.
Keywords: prior concomitant; safety; reassure; study ... See more keywords
Interim results of a phase II single arm trial combining afatinib with cetuximab in patients with EGFRex20ins positive NSCLC.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.9112
Abstract: 9112Background: Epidermal growth factor receptor exon 20 insertions (EGFRex20ins) are identified in 4-10% of all EGFR mutations in non-small cell lung cancer (NSCLC) and are associated with primary... read more here.
Keywords: interim results; arm trial; phase single; single arm ... See more keywords
Perioperative sacituzumab govitecan (SG) alone or in combination with pembrolizumab (Pembro) for patients with muscle-invasive urothelial bladder cancer (MIBC): SURE-01/02 interim results.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.17_suppl.lba4517
Abstract: LBA4517 Background: SG is an antibody-drug conjugate composed of an anti-trophoblast cell surface antigen 2 (Trop-2) antibody coupled to SN-38 (a topoisomerase-I inhibitor) with US FDA-accelerated approval for locally advanced or metastatic urothelial carcinoma (mUC).… read more here.
Keywords: interim results; response; grade; tumor ... See more keywords
Persistent morbidity in Clade IIb mpox patients: interim results of a long-term follow-up study, Belgium, June to November 2022
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DOI: 10.2807/1560-7917.es.2023.28.7.2300072
Abstract: While mpox was well characterised during the 2022 global Clade IIb outbreak, little is known about persistent morbidity. We present interim results of a prospective cohort study of 95 mpox patients assessed 3–20 weeks post-symptom… read more here.
Keywords: persistent morbidity; clade iib; interim results; mpox patients ... See more keywords
Respiratory Syncytial Virus-Load Kinetics and Clinical Course of Acute Bronchiolitis in Hospitalized Infants: Interim Results and Review of the Literature
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DOI: 10.3390/pathogens12050645
Abstract: Respiratory Syncytial Virus (RSV) bronchiolitis is the leading cause of hospitalization in infants. The role of RSV load in disease severity is still debated. We present the interim results of a prospective monocentric study enrolling… read more here.
Keywords: interim results; syncytial virus; bronchiolitis; respiratory syncytial ... See more keywords