Articles with "interleukin family" as a keyword



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Interleukin-10 Family Cytokines Immunobiology and Structure.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-13-9367-9_4

Abstract: The Interleukin (IL)-10 cytokine family includes IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26, which are considered as Class 2α-helical cytokines. IL-10 is the most important cytokine in suppressing pro-inflammatory responses in all kinds of autoimmune… read more here.

Keywords: interleukin family; immunobiology structure; family; cytokines immunobiology ... See more keywords
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Structural Insights into the Interleukin-17 Family Cytokines and Their Receptors.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-13-9367-9_5

Abstract: The IL-17 family in humans consists of six distinct cytokines (IL-17A-F) that can interact with five IL-17 receptors (IL-17RA-E). The interaction between these cytokines and their receptors are critical in mediating host defenses while also… read more here.

Keywords: cytokines receptors; interleukin family; structural insights; family ... See more keywords
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Inflammatory Profiles of the Interleukin Family and Network in Cerebral Hemorrhage

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Published in 2018 at "Cellular and Molecular Neurobiology"

DOI: 10.1007/s10571-018-0601-x

Abstract: Cerebral hemorrhage is a series of devastating cerebrovascular diseases with high mortality, morbidity and recurrence rate. Localized and systemic immuno-reactions are involved. Aggregation of immunocytes, which were both recruited from the peripheral circulation and resident in the… read more here.

Keywords: interleukin family; network; hemorrhage; cerebral hemorrhage ... See more keywords
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Interleukin (IL)-33 and the IL-1 Family of Cytokines-Regulators of Inflammation and Tissue Homeostasis.

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Published in 2019 at "Cold Spring Harbor perspectives in biology"

DOI: 10.1101/cshperspect.a028506

Abstract: Cytokines play an integral role in shaping innate and adaptive immune responses. Members of the interleukin (IL)-1 family regulate a plethora of immune-cell-mediated processes, which include pathogen defense and tissue homeostasis. Notably, the IL-1 family… read more here.

Keywords: interleukin family; tissue homeostasis; family; tissue ... See more keywords
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Interleukin‐17 family cytokines in protective immunity against infections: role of hematopoietic cell‐derived and non‐hematopoietic cell‐derived interleukin‐17s

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Published in 2018 at "Microbiology and Immunology"

DOI: 10.1111/1348-0421.12560

Abstract: Interleukin‐17 family cytokines, consisting of six members, participate in immune response in infections and autoimmune and inflammatory diseases. The prototype cytokine of the family, IL‐17A, was originally identified from CD4+ T cells which are now… read more here.

Keywords: interleukin family; cell derived; family; hematopoietic cell ... See more keywords
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Therapeutic potential of targeting interleukin‐1 family cytokines in chronic inflammatory skin diseases *

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Published in 2022 at "British Journal of Dermatology"

DOI: 10.1111/bjd.20975

Abstract: The interleukin (IL)‐1 family of cytokines is a central regulator of a myriad of immunological responses. It comprises several cytokines, including those belonging to the IL‐1, IL‐36 and IL‐18 subfamilies, as well as IL‐33. The… read more here.

Keywords: skin; family; family cytokines; inflammatory skin ... See more keywords
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The role of the interleukin‐1 family in trained immunity

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Published in 2018 at "Immunological Reviews"

DOI: 10.1111/imr.12617

Abstract: Immunological memory was long considered a trait exclusive to cells of the adaptive immune system. However, recent studies have shown that after activation of the innate immune system, innate immune cells may undergo long‐term functional… read more here.

Keywords: interleukin family; immunity; family trained; role ... See more keywords
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Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis

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Published in 2020 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2020.587929

Abstract: Kaposi’s sarcoma-associated herpesvirus (KSHV) represents the etiological agent for several human malignancies, including Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD), which are mostly seen in immunocompromised patients. In fact, KSHV… read more here.

Keywords: interleukin family; members signaling; family members; role ... See more keywords
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The Role of Interleukin-6 Family Members in Cardiovascular Diseases

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Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.818890

Abstract: Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a series of cytokines, including IL-6, IL-11, IL-30, IL-31,… read more here.

Keywords: family; members cardiovascular; family members; cardiovascular disease ... See more keywords
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The application of Interleukin-2 family cytokines in tumor immunotherapy research

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1090311

Abstract: The Interleukin-2 Family contains six kinds of cytokines, namely IL-2, IL-15, IL-4, IL-7, IL-9, and IL-21, all of which share a common γ chain. Many cytokines of the IL-2 family have been reported to be… read more here.

Keywords: application; family; tumor immunotherapy; cytokines tumor ... See more keywords
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Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer

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Published in 2022 at "Genes"

DOI: 10.3390/genes13091643

Abstract: Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses. Although IL-17 was originally identified as a cytokine that induces protective effects against bacterial and fungal infections, IL-17 can also promote chronic inflammation in a… read more here.

Keywords: cytokines metabolic; metabolic disorders; interleukin family; cancer ... See more keywords