Overexpression of ascitic interleukin-35 induces CD8+ T cell exhaustion in liver cirrhotic patients with spontaneous bacterial peritonitis.
Sign Up to like & getrecommendations! Published in 2022 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2022.108729
Abstract: Interleukin (IL) -35 induces immunotolerance by suppression of CD8+ T cells during chronic infections and cancers. In the present study, we amined to investigate the role of IL-35-mediated regulation of CD8+ T cells in patients… read more here.
Keywords: bacterial peritonitis; cd8 cells; interleukin induces; cd8 ... See more keywords
Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.02.038
Abstract: Interleukin-1 beta (IL-1β) is a pleiotropic mediator of inflammation and is produced in response to a wide range of stimuli. During infection, IL-1β production occurs in parallel with the onset of innate antimicrobial defenses, but… read more here.
Keywords: innate; induces mtdna; cgas sting; innate immune ... See more keywords
Interleukin-1β induces human cementoblasts to support osteoclastogenesis
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Oral Science"
DOI: 10.1038/ijos.2017.45
Abstract: Injury of the periodontium followed by inflammatory response often leads to root resorption. Resorption is accomplished by osteoclasts and their generation may depend on an interaction with the cells in direct contact with the root,… read more here.
Keywords: induces human; cementoblasts support; interleukin induces; human cementoblasts ... See more keywords
IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma
Sign Up to like & getrecommendations! Published in 2018 at "Autophagy"
DOI: 10.1080/15548627.2017.1421884
Abstract: ABSTRACT Allergic asthma is a common airway inflammatory disease in which B cells play important roles through IgE production and antigen presentation. SNP (single nucleotide polymorphism) analysis showed that Atg (autophagy-related) allele mutations are involved… read more here.
Keywords: il4 interleukin; induces autophagy; autophagy; autophagy cells ... See more keywords