Interleukin‐21 receptor gene polymorphism is associated with hepatitis B virus‐related hepatocellular carcinoma in Chinese patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22860
Abstract: We investigated the relationship between hepatitis B virus (HBV)‐related pathogenesis and single nucleotide polymorphisms (SNPs) in interleukin‐21 (IL‐21)‐JAK‐STAT signaling pathway genes. read more here.
Keywords: gene polymorphism; hepatitis; hepatitis virus; receptor gene ... See more keywords
Interleukin-23 receptor gene polymorphisms in Iranian patients with juvenile systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2019 at "Allergologia et immunopathologia"
DOI: 10.1016/j.aller.2019.05.007
Abstract: INTRODUCTION AND OBJECTIVES Considering the possible roles of interleukin-23 receptor (IL-23R) gene in the pathogenesis of juvenile systemic lupus erythematosus (JSLE), the objective of this study was to elucidate whether polymorphisms of the IL23R are… read more here.
Keywords: systemic lupus; lupus erythematosus; jsle; gene ... See more keywords
Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2016.11.013
Abstract: Highlights • IL-1β is a key proinflammatory cytokine involved in ischemic brain damage.• Administration of IL-1Ra improves the stroke outcome in young and co-morbid rats.• Acute IL-1Ra administration also promotes neurogenesis after experimental stroke. read more here.
Keywords: receptor antagonist; morbid; reparative effects; antagonist young ... See more keywords
Prognostic impact of Interleukin-1 receptor antagonist in patients with documented coronary artery disease.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.01.055
Abstract: BACKGROUND IL-1β-mediated inflammation contributes to development and progression of coronary artery disease (CAD). We aimed to assess the prognostic impact of the inflammatory marker Interleukin-1 receptor antagonist (IL1-Ra), reflecting high IL-1β activity, in patients with… read more here.
Keywords: receptor antagonist; patients documented; coronary artery; prognostic impact ... See more keywords
Interleukin-36 receptor antagonist is associated with the progression of renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106474
Abstract: BACKGROUNDS Renal cell carcinoma (RCC) is the most predominant type of kidney neoplasms. One of the major inducers of RCC is the uncontrolled inflammation responses, which promotes the development, progression and metastasis of RCC. Thus,… read more here.
Keywords: receptor antagonist; renal cell; cell carcinoma; rcc ... See more keywords
Drug-induced sarcoidosis in a patient treated with an interleukin-1 receptor antagonist for hidradenitis suppurativa
Sign Up to like & getrecommendations! Published in 2018 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2018.03.007
Abstract: IFN: interferon IL: interleukin IL-1Ra: interleukin-1 receptor antagonist Th1: T helper cell type 1 TNF: tumor necrosis factor INTRODUCTION Numerous reports document cases of iatrogenic sarcoidosis or sarcoidlike granulomatosis in the setting of biologic therapy… read more here.
Keywords: receptor antagonist; sarcoidosis; interleukin receptor; patient ... See more keywords
Interleukin 1 receptor antagonist and 2'-5'-oligoadenylate synthetase-like molecules as novel biomarkers for multiple sclerosis patients in Bahrain.
Sign Up to like & getrecommendations! Published in 2017 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2017.09.001
Abstract: BACKGROUND Multiple sclerosis (MS) is a multi-factorial disease of the Central Nervous System (CNS) affecting young adults leading to significant disabilities over time. MS is now believed to be prevalent in Arabian Gulf area with… read more here.
Keywords: sclerosis; patients control; patients bahrain; multiple sclerosis ... See more keywords
Interleukin-1 receptor antagonist: An exploratory plasma biomarker that correlates with disabilty and provides pathophysiological insights in relapsing-remitting multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2021.103006
Abstract: BACKGROUND Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative disorder. Interleukin-1 receptor antagonist (IL-1RA) is an endogenous soluble antagonist of the IL-1 receptor and blocks the pro-inflammatory effects of IL-1β known to contribute… read more here.
Keywords: receptor antagonist; sclerosis; relapsing remitting; multiple sclerosis ... See more keywords
Measurement of the concentration of serum soluble interleukin-2 receptor alpha chain in dogs with lymphoma.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2020.110054
Abstract: Soluble interleukin-2 receptor (sIL-2r) is released directly from the surface of lymphocytes expressing interleukin-2 receptor alpha chain (CD25), and its serum concentration has been found to reflect the prognosis of human lymphoproliferative malignancies. In this… read more here.
Keywords: serum sil; serum; concentration; interleukin receptor ... See more keywords
Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b01078
Abstract: Sterile alpha and toll/interleukin receptor (TIR) motif-containing protein 1 (SARM1) plays a pivotal role in triggering the neurodegenerative processes that underlie peripheral neuropathies, traumatic brain injury, and neurodegenerative diseases. Importantly, SARM1 knock down or knock… read more here.
Keywords: alpha toll; toll interleukin; motif containing; interleukin receptor ... See more keywords
How Can Interleukin-1 Receptor Antagonist Modulate Distinct Cell Death Pathways?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00565
Abstract: Multiple mechanisms of cell death exist (apoptosis, necroptosis, pyroptosis) and the subtle balance of several distinct proteins and inhibitors tightly regulates the cell fate toward one or the other pathway. Here, by combining coimmunoprecipitation, enzyme… read more here.
Keywords: receptor antagonist; death; interleukin receptor; cell death ... See more keywords