Scalable synthesis of a tetrasubstituted 7-azabenzofuran as a key intermediate for a class of potent HCV NS5B inhibitors
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DOI: 10.1016/j.tet.2020.131642
Abstract: Abstract A series of tetrasubstituted 7-azabenzofurans displays remarkable pan-genotype inhibition of HCV NS5B polymerase. One of them has been identified as a potential clinical candidate. Completely different from the original synthesis of a common and… read more here.
Keywords: hcv ns5b; key intermediate; intermediate class; synthesis ... See more keywords