Assembly studies of six intestinal intermediate filament (IF) proteins B2, C1, C2, D1, D2, and E1 in the nematode C. elegans
Sign Up to like & getrecommendations! Published in 2017 at "Cytoskeleton"
DOI: 10.1002/cm.21354
Abstract: The dimerisation properties of six intestine‐expressed intermediate filament (IF) proteins (B2, C1, C2, D1, D2, E1) were analysed in blot overlay assay on membranes containing all of the eleven recombinant C. elegans IF proteins (A1,… read more here.
Keywords: filament proteins; six intestinal; assembly studies; studies six ... See more keywords
The stable brother hiding in the shadow—news on intermediate filaments
Sign Up to like & getrecommendations! Published in 2020 at "Protoplasma"
DOI: 10.1007/s00709-020-01541-w
Abstract: The term “cytoskeleton” has been coined, when, from the early 1960s, electron microscopy has revealed filamentous structures that seemed to organise the cytoplasm (“microtubules”, Ledbetter and Porter 1963; “microfilaments”, Kamiya and Kuroda 1966). Onlywith the… read more here.
Keywords: plant; beak; egg; intermediate filaments ... See more keywords
Keratin Intermediate Filament Chains in the European Common Wall Lizard (Podarcis muralis) and a Potential Keratin Filament Crosslinker.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2021.107793
Abstract: On the basis of sequence homology with mammalian α-keratins, and on the criteria that the coiled-coil segments and central linker in the rod domain of these molecules must have conserved lengths if they are to… read more here.
Keywords: intermediate filament; keratin intermediate; wall lizard; filament ... See more keywords
Tuning intermediate filament mechanics by variation of pH and ion charges.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr02778b
Abstract: The cytoskeleton is formed by three types of filamentous proteins - microtubules, actin filaments, and intermediate filaments (IFs) - and enables cells to withstand external and internal forces. Vimentin is the most abundant IF protein… read more here.
Keywords: tuning intermediate; filament mechanics; mechanical properties; ion ... See more keywords
The next generation of protein super‐fibres: robust recombinant production and recovery of hagfish intermediate filament proteins with fibre spinning and mechanical–structural characterizations
Sign Up to like & getrecommendations! Published in 2021 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13869
Abstract: Native hagfish intermediate filament proteins have impressive mechanical properties. However, using these native fibres for any application is impractical, necessitating their recombinant production. In the only literature report on the proteins (denoted α and ɣ),… read more here.
Keywords: intermediate filament; hagfish intermediate; recombinant production; filament proteins ... See more keywords
Paraneoplastic neuronal intermediate filament autoimmunity
Sign Up to like & getrecommendations! Published in 2018 at "Neurology"
DOI: 10.1212/wnl.0000000000006435
Abstract: Objective To describe paraneoplastic neuronal intermediate filament (NIF) autoimmunity. Methods Archived patient and control serum and CSF specimens were evaluated by tissue-based indirect immunofluorescence assay (IFA). Autoantigens were identified by Western blot and mass spectrometry.… read more here.
Keywords: neuronal intermediate; autoimmunity; nfl igg; intermediate filament ... See more keywords
Noise-induced hearing loss vulnerability in type III intermediate filament peripherin gene knockout mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.962227
Abstract: In the post-natal mouse cochlea, type II spiral ganglion neurons (SGNs) innervating the electromotile outer hair cells (OHCs) of the ‘cochlear amplifier' selectively express the type III intermediate filament peripherin gene (Prph). Immunolabeling showed that… read more here.
Keywords: filament peripherin; type; type iii; iii intermediate ... See more keywords
Skeletal and Cardiac Muscle Disorders Caused by Mutations in Genes Encoding Intermediate Filament Proteins
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084256
Abstract: Intermediate filaments are major components of the cytoskeleton. Desmin and synemin, cytoplasmic intermediate filament proteins and A-type lamins, nuclear intermediate filament proteins, play key roles in skeletal and cardiac muscle. Desmin, encoded by the DES… read more here.
Keywords: muscle disorders; filament proteins; muscle; skeletal cardiac ... See more keywords
Role of the Intermediate Filament Protein Peripherin in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315416
Abstract: Intermediate filaments are the most heterogeneous class among cytoskeletal elements. While some of them have been well-characterized, little is known about peripherin. Peripherin is a class III intermediate filament protein with a specific expression in… read more here.
Keywords: filament protein; role; peripherin; intermediate filament ... See more keywords
The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.66143
Abstract: The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in regulating other aspects of cardiac… read more here.
Keywords: myocardial wall; intermediate filament; wall integrity; transcription factor ... See more keywords
Capturing intermediate filament networks
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.78248
Abstract: Mapping intermediate filaments in three dimensions reveals that the organization of these filaments differs across cell types. read more here.
Keywords: intermediate filament; capturing intermediate; filament networks;