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   Articles with "intermediate filaments" as a keyword



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Intermediate filaments in developing neurons: Beyond structure

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recommendations! Published in 2020 at "Cytoskeleton"

DOI: 10.1002/cm.21597

Abstract: Neuronal development relies on a highly choreographed progression of dynamic cellular processes by which newborn neurons migrate, extend axons and dendrites, innervate their targets, and make functional synapses. Many of these dynamic processes require coordinated… read more here.

Keywords: developing neurons; intermediate filaments; beyond structure; neurons beyond ... See more keywords
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The stable brother hiding in the shadow—news on intermediate filaments

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recommendations! Published in 2020 at "Protoplasma"

DOI: 10.1007/s00709-020-01541-w

Abstract: The term “cytoskeleton” has been coined, when, from the early 1960s, electron microscopy has revealed filamentous structures that seemed to organise the cytoplasm (“microtubules”, Ledbetter and Porter 1963; “microfilaments”, Kamiya and Kuroda 1966). Onlywith the… read more here.

Keywords: plant; beak; egg; intermediate filaments ... See more keywords
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Intermediate filaments in cardiomyopathy

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recommendations! Published in 2018 at "Biophysical Reviews"

DOI: 10.1007/s12551-018-0443-2

Abstract: Intermediate filament (IF) proteins are critical regulators in health and disease. The discovery of hundreds of mutations in IF genes and posttranslational modifications has been linked to a plethora of human diseases, including, among others,… read more here.

Keywords: protein; filaments cardiomyopathy; heart; intermediate filaments ... See more keywords
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Effect of Divalent Cations on the Structure and Mechanics of Vimentin Intermediate Filaments.

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recommendations! Published in 2020 at "Biophysical journal"

DOI: 10.1016/j.bpj.2020.05.016

Abstract: Divalent cations behave as effective cross-linkers of intermediate filaments (IFs) such as vimentin IF (VIF). These interactions have been mostly attributed to their multivalency. However, ion-protein interactions often depend on the ion species, and these… read more here.

Keywords: divalent cations; effect; intermediate filaments; structure mechanics ... See more keywords
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Model for Bundling of Keratin Intermediate Filaments

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recommendations! Published in 2020 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2020.05.024

Abstract: Keratin intermediate filaments form dynamic intracellular networks, which span the entire cytoplasm and provide mechanical strength to the cell. The mechanical resilience of the keratin intermediate filament network itself is determined by filament bundling. The… read more here.

Keywords: bundling keratin; keratin intermediate; intermediate filaments; model bundling ... See more keywords
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Drugs targeting intermediate filaments can improve neurosupportive properties of astrocytes

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recommendations! Published in 2018 at "Brain Research Bulletin"

DOI: 10.1016/j.brainresbull.2017.01.021

Abstract: In response to central nervous system (CNS) injury, astrocytes upregulate intermediate filament (nanofilament) proteins GFAP and vimentin. Whereas the intermediate filament upregulation in astrocytes is important for neuroprotection in the acute phase of injury, in… read more here.

Keywords: drugs targeting; clomipramine epoxomicin; targeting intermediate; neurosupportive properties ... See more keywords
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Volt-ampere characteristics of porcine retinal Müller cell intermediate filaments

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recommendations! Published in 2020 at "Chemical Physics"

DOI: 10.1016/j.chemphys.2019.110532

Abstract: Abstract In the current study we reported current-voltage (I/V) characteristics of Muller cell (MC) intermediate filaments (IFs) isolated from porcine retina. It was found that the measured I/V dependences demonstrate behavior of a semiconductor in… read more here.

Keywords: cell intermediate; electric conductivity; intermediate filaments; cell ... See more keywords
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Vimentin Intermediate Filaments Undergo Irreversible Conformational Changes during Cyclic Loading.

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recommendations! Published in 2019 at "Nano letters"

DOI: 10.1021/acs.nanolett.9b02972

Abstract: Intermediate filaments (IFs) are part of the cytoskeleton of eukaryotic cells and, therefore, are largely responsible for the cell's mechanical properties. IFs are characterized by a pronounced extensibility and remarkable resilience that enable them to… read more here.

Keywords: irreversible conformational; undergo irreversible; filaments undergo; intermediate filaments ... See more keywords
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Post-translational modifications soften vimentin intermediate filaments.

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recommendations! Published in 2020 at "Nanoscale"

DOI: 10.1039/d0nr07322a

Abstract: The mechanical properties of biological cells are determined by the cytoskeleton, a composite biopolymer network consisting of microtubules, actin filaments and intermediate filaments (IFs). By differential expression of cytoskeletal proteins, modulation of the network architecture… read more here.

Keywords: modifications soften; soften vimentin; post translational; intermediate filaments ... See more keywords
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Ion type and valency differentially drive vimentin tetramers into intermediate filaments or higher order assemblies.

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recommendations! Published in 2020 at "Soft matter"

DOI: 10.1039/d0sm01659d

Abstract: Vimentin intermediate filaments, together with actin filaments and microtubules, constitute the cytoskeleton in cells of mesenchymal origin. The mechanical properties of the filaments themselves are encoded in their molecular architecture and depend on their ionic… read more here.

Keywords: vimentin; type valency; higher order; ion type ... See more keywords
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Intermediate filaments ensure resiliency of single carcinoma cells, while active contractility of the actin cortex determines their invasive potential

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recommendations! Published in 2021 at "New Journal of Physics"

DOI: 10.1088/1367-2630/ac1899

Abstract: During the epithelial-to-mesenchymal transition, the intracellular cytoskeleton undergoes severe reorganization which allows epithelial cells to transition into a motile mesenchymal phenotype. Among the different cytoskeletal elements, the intermediate filaments keratin (in epithelial cells) and vimentin… read more here.

Keywords: resiliency single; carcinoma; ensure resiliency; intermediate filaments ... See more keywords