Articles with "intermediate phenotypes" as a keyword



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T13 Gwas Of Bsnip Biofactors And Biotypes As Intermediate Phenotypes For Psychosis

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Published in 2017 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2016.09.501

Abstract: Background The Bipolar and Schizophrenia Network of Intermediate Phenotypes (BSNIP) is an ongoing NIMH-funded study aimed to identify biomarker-based classification of psychoses, with clinical, imaging and neurophysiological phenotypes, consistent with Research Domain Criteria. Analyses of… read more here.

Keywords: bsnip; intermediate phenotypes; analysis; t13 gwas ... See more keywords
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Associations of retinal microvascular caliber with intermediate phenotypes of large arterial function and structure: A systematic review and meta‐analysis

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Published in 2019 at "Microcirculation"

DOI: 10.1111/micc.12557

Abstract: Intermediate phenotypes of microcirculation (retinal microvascular caliber) are associated with cardiovascular (CV) risk factors and independently predict CV events. However, the effect of microcirculation variation on the vascular system is unclear. We conducted a systematic… read more here.

Keywords: retinal microvascular; review meta; intermediate phenotypes; systematic review ... See more keywords
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Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes

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Published in 2019 at "PLoS ONE"

DOI: 10.1371/journal.pone.0217189

Abstract: Genome-wide association studies (GWAS) have been successful in identifying genetic variants associated with complex diseases. However, association analyses between genotypes and phenotypes are not straightforward due to the complex relationships between genetic and environmental factors.… read more here.

Keywords: snps; equation modeling; intermediate phenotypes; structural equation ... See more keywords
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Mini-Review: The Contribution of Intermediate Phenotypes to GxE Effects on Disorders of Body Composition in the New OMICS Era

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Published in 2017 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph14091079

Abstract: Studies of gene-environment (GxE) interactions describe how genetic and environmental factors influence the risk of developing disease. Intermediate (molecular or clinical) phenotypes (IPs) are traits or metabolic biomarkers that mediate the effects of gene-environment influences… read more here.

Keywords: mini review; contribution intermediate; intermediate phenotypes; body composition ... See more keywords