Articles with "intermediate purification" as a keyword



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Intermediate purification of CHO‐derived recombinant human Factor IX using hydrophobic interaction membrane‐based chromatography and its comparison to a sulfated resin

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Published in 2017 at "ELECTROPHORESIS"

DOI: 10.1002/elps.201700226

Abstract: This work investigated the use of hydrophobic interaction membrane chromatography for intermediate purification of recombinant human Factor IX (rFIX) produced by CHO cells. The first purification step was based on a strong anion exchange monolith,… read more here.

Keywords: hydrophobic interaction; recombinant human; factor; intermediate purification ... See more keywords
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Design of a Combined Modular and 3D-Printed Falling Film Solution Layer Crystallizer for Intermediate Purification in Continuous Production of Pharmaceuticals

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Published in 2021 at "Industrial & Engineering Chemistry Research"

DOI: 10.1021/acs.iecr.1c00988

Abstract: A highly scalable combined modular and 3D-printed falling film crystallization device is developed and demonstrated herein; the device uses a small, complex, printed overflow-based film distribution part that ensures formation of a well-distributed heated liquid… read more here.

Keywords: combined modular; modular printed; crystallizer; intermediate purification ... See more keywords