Ethylenediaminetetraacetic Acid Enhances Vancomycin and Reactive Oxygen Species–Mediated Killing of Vancomycin-Intermediate Staphylococcus aureus
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DOI: 10.1093/ofid/ofaf291
Abstract: Abstract Background The emergence of antibiotic-tolerant staphylococcal strains, such as vancomycin-intermediate Staphylococcus aureus (VISA), poses a significant healthcare challenge and complicates treatment regimens. VISA often exhibits mutations in Krebs cycle enzymes, promoting anaerobic metabolism under… read more here.
Keywords: intermediate staphylococcus; visa; mediated killing; staphylococcus aureus ... See more keywords
The combined antibacterial effects of sodium new houttuyfonate and berberine chloride against growing and persistent methicillin-resistant and vancomycin-intermediate Staphylococcus aureus
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DOI: 10.1186/s12866-020-02003-2
Abstract: Background Infections caused by drug-resistant Staphylococcus aureus , especially vancomycin-intermediate Staphylococcus aureus (VISA), leave clinicians with limited therapeutic options for treatment. Persister cells is a leading cause of recalcitrant infection and antibiotic treatment failure, and… read more here.
Keywords: staphylococcus aureus; vancomycin intermediate; aureus; snh ... See more keywords
Emerging Antimicrobial Strategies Against Heterogeneous and Vancomycin-Intermediate Staphylococcus aureus
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DOI: 10.2147/ijgm.s532471
Abstract: Abstract Heterogeneous vancomycin-intermediate and vancomycin-intermediate Staphylococcus aureus (hVISA and VISA) presents significant therapeutic challenges due to high treatment failure rates and limited options. Conventional monotherapies, including daptomycin and linezolid, are often compromised by cross-resistance and… read more here.
Keywords: intermediate staphylococcus; heterogeneous vancomycin; emerging antimicrobial; staphylococcus aureus ... See more keywords