Intermolecular amination of allylic and benzylic alcohols leads to effective inhibitions of acetylcholinesterase enzyme and carbonic anhydrase I and II isoenzymes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22173
Abstract: In this study, we aimed to determine the inhibition effects of novel synthesized sulfamates (2a–g), sulfonamides (3b–f), carbonyl sulfonamides (3h and i), and carbonyl sulfamates (4h and 4i), which were tested against two human cytosolic… read more here.
Keywords: carbonic anhydrase; inhibition; intermolecular amination; amination allylic ... See more keywords
Enantioselective Intermolecular C–H Amination Directed by a Chiral Cation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c05206
Abstract: The enantioselective amination of C(sp3)–H bonds is a powerful synthetic transformation yet highly challenging to achieve in an intermolecular sense. We have developed a family of anionic variants of the best-in-class catalyst for Rh-catalyzed C–H… read more here.
Keywords: enantioselective intermolecular; cation; intermolecular amination; amination directed ... See more keywords