Anti-tumor activity of anthrax toxin variants that form a functional translocation pore by intermolecular complementation.
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DOI: 10.18632/oncotarget.17729
Abstract: Anthrax lethal toxin is a typical A-B type protein toxin secreted by Bacillus anthracis. Lethal factor (LF) is the catalytic A-subunit, a metalloprotease having MEKs as targets. LF relies on the cell-binding B-subunit, protective antigen… read more here.
Keywords: form functional; intermolecular complementation; toxin; pore ... See more keywords