Intermolecular [2 + 2] Cycloaddition of 1,4-Dihydropyridines with Olefins via Energy Transfer.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02881
Abstract: A highly regio- and diastereoselective visible-light-promoted [2 + 2] cycloaddition between readily available 1,4-dihydropyridines and olefins has been developed. This strategy is operationally simple and atom-economical and enables the construction of strained polysubstituted 2-azabicyclo[4.2.0]octanes with… read more here.
Keywords: cycloaddition dihydropyridines; energy transfer; intermolecular cycloaddition; dihydropyridines olefins ... See more keywords
Acid-promoted intra- and intermolecular [2+2] cycloaddition of indoles to aryl alkynes to access cyclobutene-fused indolines.
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DOI: 10.1039/d2cc02840a
Abstract: Herein, we have reported the first example of both intra- and intermolecular [2+2] cycloaddition of the electron-rich indoles and unactivated aryl alkynes promoted by the combination of Fe(NO3)3 and HNO3, which highlights efficient and selective… read more here.
Keywords: fused indolines; cyclobutene fused; intermolecular cycloaddition; aryl alkynes ... See more keywords
An umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles
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DOI: 10.1039/d2sc00046f
Abstract: We have described the first example of an umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition between two aryl aldehydes and a nitrile under the influence of TMSOTf that proceeds through the formation… read more here.
Keywords: strategy intermolecular; intermolecular cycloaddition; trisubstituted oxazoles; umpolung strategy ... See more keywords
An efficient heterogeneous gold(I)-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes leading to polyfunctionalized quinolines
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DOI: 10.1080/00397911.2019.1567788
Abstract: Abstract The first heterogeneous intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes was realized in DMF at 100 °C by using a triphenylphosphine-functionalized MCM-41-supported gold(I) complex [MCM-41-PPh3-AuCl] and AgOTf as catalysts, yielding a variety of polyfunctionalized… read more here.
Keywords: internal alkynes; aminoaryl carbonyls; intermolecular cycloaddition; cycloaddition aminoaryl ... See more keywords