Asymmetric Organocatalyzed Intermolecular Functionalization of Cyclohexanone-Derived Dienones.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical record"
DOI: 10.1002/tcr.202300042
Abstract: Over the past decades, the advent of asymmetric organocatalysis has changed the way chemists think about creating or breaking chemical bonds, enabling new enantioselective strategies for functionalized molecules. The success of asymmetric organocatalysis is notably… read more here.
Keywords: cyclohexanone derived; derived dienones; intermolecular functionalization; cyclohexanone ... See more keywords
Intermolecular α-Functionalization of Benzylamides with N-Nucleophiles via Oxidative Umpolung: Synthesis of Tetrasubstituted 3,3'-Oxindoles.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c02167
Abstract: A hypervalent iodine-mediated intermolecular α-umpolung reaction between α-aryl- or alkyl-substituted amides and benzotriazoles or purine derivatives as N-centered nucleophiles has been established. The reaction involves sequential intra/intermolecular oxidative C-N couplings in a controlled manner, affording… read more here.
Keywords: via oxidative; functionalization benzylamides; benzylamides nucleophiles; nucleophiles via ... See more keywords