Existence of Internal N7-Methylguanosine Modification in mRNA Determined by Differential Enzyme Treatment Coupled with Mass Spectrometry Analysis.
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DOI: 10.1021/acschembio.7b00906
Abstract: The recent discovery of reversible chemical modifications on mRNA has opened a new era of post-transcriptional gene regulation in eukaryotes. Among the 15 types of modifications identified in mRNA of eukaryotes, N7-methylguanosine (m7G) is unique… read more here.
Keywords: spectrometry analysis; internal m7g; m7g; mass spectrometry ... See more keywords