Copper-Catalyzed Enantioselective Cyclopropanation of Internal Olefins with Diazomalonates.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02694
Abstract: The first enantioselective copper catalyzed cyclopropanation of internal olefins with diazomalonates is reported. This process provides a new method for the synthesis of chiral 1,1-cyclopropane diesters. With a chiral bi-side arm bisoxazoline-copper(I) complex, the reaction… read more here.
Keywords: cyclopropanation internal; catalyzed enantioselective; olefins diazomalonates; copper catalyzed ... See more keywords
Trans-selective cyclizations of alpha-bromocarboxamides and E/Z-mixed internal olefins catalyzed by a Fe salt.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04796a
Abstract: There are several reports of lactam cyclizations, but most yield less-substituted lactam rings. Therefore, diastereoselective cyclization to yield highly substituted lactams is one of the challenges in this field. We therefore propose a strategy involving… read more here.
Keywords: selective cyclizations; alpha bromocarboxamides; internal olefins; trans selective ... See more keywords