P6497Loeys-Dietz syndrome-5: phenotypic spectrum of TGFB3 mutations in an international cohort and first report of a homozygous patient
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DOI: 10.1093/eurheartj/ehz746.1087
Abstract: Mutations in TGFB3 cause Loeys-Dietz syndrome-5 (LDS5), an autosomal dominantly inherited connective tissue disorder. LDS5 is characterized by aortic aneurysms and dissections associated with systemic features mainly involving the ocular and skeletal systems. Precise delineation… read more here.
Keywords: tgfb3 mutations; lds5; international cohort; dietz syndrome ... See more keywords
An International Cohort Study of Prognosis Associated With Pathologically Complete Response Following Neoadjuvant Chemotherapy Versus Chemoradiotherapy of Surgical Treated Esophageal Adenocarcinoma
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DOI: 10.1097/sla.0000000000005619
Abstract: Objective: To compare overall (OS) and recurrence-free survival (RFS) in esophageal adenocarcinoma patients with a pathologically complete response (pCR) following neoadjuvant chemotherapy (nCT) or neoadjuvant chemoradiotherapy (nCRT). Background: In the absence of survival differences in… read more here.
Keywords: chemoradiotherapy; following neoadjuvant; international cohort; cohort study ... See more keywords
Selfâreported cognitive function in a large international cohort of people with multiple sclerosis: associations with lifestyle and other factors
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DOI: 10.1111/ene.13784
Abstract: We aimed to estimate the prevalence of perceived cognitive impairment (PCI) and explore its associations with lifestyle and disease characteristics in a large international cohort of people with multiple sclerosis (MS). read more here.
Keywords: multiple sclerosis; cohort people; associations lifestyle; international cohort ... See more keywords
International cohort study indicates no association between alpha-1 blockers and susceptibility to COVID-19 in benign prostatic hyperplasia patients
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DOI: 10.3389/fphar.2022.945592
Abstract: Purpose: Alpha-1 blockers, often used to treat benign prostatic hyperplasia (BPH), have been hypothesized to prevent COVID-19 complications by minimising cytokine storm release. The proposed treatment based on this hypothesis currently lacks support from reliable… read more here.
Keywords: alpha blockers; international cohort; cohort study; alpha ... See more keywords