Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
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DOI: 10.1038/onc.2016.485
Abstract: Epigenetic and metabolic alterations in cancer cells are highly intertwined. Oncogene-driven metabolic rewiring modifies the epigenetic landscape via modulating the activities of DNA and histone modification enzymes at the metabolite level. Conversely, epigenetic mechanisms regulate… read more here.
Keywords: epigenetics metabolism; oncogenesis mechanisms; mechanisms therapeutic; metabolism ... See more keywords
Interplay between Epigenetics and Cellular Metabolism in Colorectal Cancer
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DOI: 10.3390/biom11101406
Abstract: Cellular metabolism alterations have been recognized as one of the most predominant hallmarks of colorectal cancers (CRCs). It is precisely regulated by many oncogenic signaling pathways in all kinds of regulatory levels, including transcriptional, post-transcriptional,… read more here.
Keywords: metabolism; cellular metabolism; interplay epigenetics; metabolic enzymes ... See more keywords