The interplay between glioblastoma and microglia cells leads to endothelial cell monolayer dysfunction via the interleukin‐6‐induced JAK2/STAT3 pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28575
Abstract: Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor, with an average life expectancy of 12–15 months. GBM is highly infiltrated by microglial cells (MG) promoting tumor growth and invasiveness. Moreover, microglia… read more here.
Keywords: interplay glioblastoma; glioblastoma; dysfunction; microglia cells ... See more keywords
Epigenetics and Metabolism Reprogramming Interplay into Glioblastoma: Novel Insights on Immunosuppressive Mechanisms
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020220
Abstract: The central nervous system represents a complex environment in which glioblastoma adapts skillfully, unleashing a series of mechanisms suitable for its efficient development and diffusion. In particular, changes in gene expression and mutational events that… read more here.
Keywords: glioblastoma novel; glioblastoma; epigenetics metabolism; interplay glioblastoma ... See more keywords