Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Sign Up to like & getrecommendations! Published in 2020 at "Science advances"
DOI: 10.1126/sciadv.aba0647
Abstract: While N 6-methyladenosine (m6A) is the most prevalent modification of eukaryotic messenger RNA (mRNA) involved in various cellular responses, its role in modulating bacteria-induced inflammatory response remains elusive. Here, we showed that loss of the… read more here.
Keywords: trimethylation; bacterial infection; h3k27me3; m6a ... See more keywords
Interplay between the m6A Epitranscriptome and Tumor Metabolism: Mechanisms and Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10102589
Abstract: N6-methyladenosine (m6A) modification of messenger RNA (mRNA) influences the stability and translation of the transcripts into functional proteins. Recent studies reveal the role of m6A modifications in regulating the metabolism of basic biomolecules such as… read more here.
Keywords: metabolism; m6a epitranscriptome; therapeutic implications; interplay m6a ... See more keywords