Thymoquinone alleviates renal interstitial fibrosis and kidney dysfunction in rats with unilateral ureteral obstruction
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6376
Abstract: Unilateral ureteral obstruction (UUO) causes severe renal tubulointerstitial fibrosis. Because of many pharmacologic properties of thymoquinone (TQ), in this study, the effects of TQ against kidney fibrosis and dysfunction were investigated in rats with UUO.… read more here.
Keywords: unilateral ureteral; interstitial fibrosis; ureteral obstruction; fibrosis ... See more keywords
Chrysin attenuates interstitial fibrosis and improves cardiac function in a rat model of acute myocardial infarction
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-018-9793-0
Abstract: Interstitial fibrosis after acute myocardial infarction (MI) leads to cardiac structural remodeling and dysfunction. The peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonist chrysin has been shown to protect injured myocardium through suppression of oxidative stress and inflammation.… read more here.
Keywords: interstitial fibrosis; fibrosis; myocardial infarction; chrysin ... See more keywords
B lymphocytes in renal interstitial fibrosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-017-0382-x
Abstract: Fibrosis is defined as an excessive deposition of extracellular matrix (ECM), which leads to the destruction of organ structure and impairment of organ function. Fibrosis occurs not only in kidney but also in lung, liver,… read more here.
Keywords: interstitial fibrosis; lymphocytes renal; fibrosis; renal interstitial ... See more keywords
The extent of tubulointerstitial inflammation is an independent predictor of renal survival in lupus nephritis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Nephrology"
DOI: 10.1007/s40620-021-01007-z
Abstract: Lupus nephritis (LN) is a major complication in patients with systemic lupus erythematosus (SLE). Tubulointerstitial injury is an inflammatory process that, if not attenuated, can promote renal damage. Despite this, the current 2003 ISN/RPS “glomerulocentric”… read more here.
Keywords: fibrosis tubular; interstitial fibrosis; inflammation; renal survival ... See more keywords
Chrysophanol ameliorates renal interstitial fibrosis by inhibiting the TGF-β/Smad signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114079
Abstract: Renal interstitial fibrosis (RIF) is a major pathological feature of chronic kidney disease at middle and end stages. Chrysophanol (CP), 1,8-dihydroxy-3-methyl-9,10-anthraquinone, is an anthraquinone isolated from Rheum palmatum L.with a variety of pharmacological activities including… read more here.
Keywords: interstitial fibrosis; fibrosis; tgf smad; tgf ... See more keywords
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112856
Abstract: Renal interstitial fibrosis (RIF) is the common irreversible pathway by which chronic kidney disease (CKD) progresses to the end stage. The transforming growth factor-β (TGF-β)/signal transducer and activator of transcription 3 (STAT3) signaling pathway is… read more here.
Keywords: interstitial fibrosis; saa1; endoplasmic reticulum; reticulum stress ... See more keywords
Tubular atrophy/interstitial fibrosis scores of Oxford classification combinded with proteinuria level at biopsy provides earlier risk prediction in lgA nephropathy
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-01223-3
Abstract: The predictive effect of combining MEST with clinical data at biopsy on renal survival outcomes has not been investigated in patients with IgA nephropathy (IgAN). MEST of The Oxford classification of IgAN and 24-hour urine… read more here.
Keywords: biopsy; classification; interstitial fibrosis; oxford classification ... See more keywords
The Significance of Interstitial Fibrosis on Left Ventricular Function in Hypertensive versus Hypertrophic Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27049-1
Abstract: Extracellular volume (ECV) has been validated as a surrogate measure of interstitial fibrosis, that is increased in both hypertension-induced left ventricular hypertrophy (H-LVH) and hypertrophic cardiomyopathy (HCM). We aimed to explore the correlation between ECV… read more here.
Keywords: ecv; interstitial fibrosis; hypertrophic cardiomyopathy; function ... See more keywords
Pathologic features of smoking-related lung diseases, with emphasis on smoking-related interstitial fibrosis and a consideration of differential diagnoses.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2018.08.002
Abstract: Smoking-related interstitial fibrosis (SRIF) is frequently-seen and morphologically-distinctive finding in the lung tissue of cigarette smokers. It can be distinguished histologically from the idiopathic interstitial pneumonias and other causes of pulmonary interstitial fibrosis. SRIF is… read more here.
Keywords: interstitial fibrosis; pathologic features; related interstitial; smoking related ... See more keywords
Kidney tissue elastography and interstitial fibrosis observed in kidney biopsy
Sign Up to like & getrecommendations! Published in 2022 at "Renal Failure"
DOI: 10.1080/0886022x.2022.2035763
Abstract: Abstract Introduction Kidney interstitial fibrosis is an important risk factor for the progression of chronic kidney disease. Kidney elastography is a noninvasive imaging modality that might be used to assess tissue fibrosis. In this study,… read more here.
Keywords: kidney biopsy; interstitial fibrosis; kidney; elastography ... See more keywords
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2097700
Abstract: Abstract Context Baicalin, a flavonoid extracted from radix scutellariae, possesses various pharmacological effects, including protective effects on renal interstitial fibrosis (RIF), but its possible role and mechanisms have not been fully elucidated. Objective This study… read more here.
Keywords: baicalin; tgf smad; interstitial fibrosis; mice ... See more keywords