Engineered Microneedles for Interstitial Fluid Cell‐Free DNA Capture and Sensing Using Iontophoretic Dual‐Extraction Wearable Patch
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202000591
Abstract: Interstitial fluid (ISF), as an emerging source of biomarkers, is unmistakably significant for disease diagnosis. Microneedles (MNs) provide a minimally invasive approach for extracting the desired molecules from ISF. However, existing MNs are limited by… read more here.
Keywords: free dna; capture; interstitial fluid; cell free ... See more keywords
Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801262
Abstract: Interstitial fluid (ISF) that surrounds cells in tissues of the body is a novel source of biomarker that complements conventional sources like blood, urine, and saliva. To overcome difficulties in harvesting ISF, a minimally invasive,… read more here.
Keywords: isf; interstitial fluid; patch; microneedle patch ... See more keywords
Microneedle Patch for Painless Intradermal Collection of Interstitial Fluid Enabling Multianalyte Measurement of Small Molecules, SARS‐CoV‐2 Antibodies, and Protein Profiling
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202564
Abstract: Blood sampling is a common practice to monitor health, but it entails a series of drawbacks for patients including pain and discomfort. Thus, there is a demand for more convenient ways to obtain samples. Modern… read more here.
Keywords: microneedle patch; cov antibodies; painless; interstitial fluid ... See more keywords
An optimized b‐value sampling for the quantification of interstitial fluid using diffusion‐weighted MRI, a genetic algorithm approach
Sign Up to like & getrecommendations! Published in 2023 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29612
Abstract: Multi‐b‐value diffusion‐weighted MRI techniques can simultaneously measure the parenchymal diffusivity, microvascular perfusion, and a third, intermediate diffusion component. This component is related to the interstitial fluid in the brain parenchyma. However, simultaneously estimating three diffusion… read more here.
Keywords: diffusion weighted; diffusion; value; interstitial fluid ... See more keywords
Parametric study of 3D printed microneedle (MN) holders for interstitial fluid (ISF) extraction
Sign Up to like & getrecommendations! Published in 2020 at "Microsystem Technologies"
DOI: 10.1007/s00542-020-04758-0
Abstract: The need for novel, minimally invasive diagnostic, prognostic, and therapeutic biomedical devices has garnered increased interest in recent years. Microneedle (MN) technology has stood out as a promising new method for drug delivery, as well as… read more here.
Keywords: extraction; interstitial fluid; isf extraction; fluid isf ... See more keywords
Fabrication of sponge-forming microneedle patch for rapidly sampling interstitial fluid for analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical microdevices"
DOI: 10.1007/s10544-019-0413-x
Abstract: Microneedle (MN) patch has been used for collecting dermal interstitial fluid (ISF) containing biomarkers from patients with safety, pain-free and easy-to-use manner. However, long sampling time for biomarkers analysis still poses a significant challenge. Here,… read more here.
Keywords: sponge forming; analysis; patch; interstitial fluid ... See more keywords
Imaging for central nervous system (CNS) interstitial fluidopathy: disorders with impaired interstitial fluid dynamics
Sign Up to like & getrecommendations! Published in 2020 at "Japanese Journal of Radiology"
DOI: 10.1007/s11604-020-01017-0
Abstract: After the introduction of the glymphatic system hypothesis, an increasing number of studies on cerebrospinal fluid and interstitial fluid dynamics within the brain have been investigated and reported. A series of diseases are known which… read more here.
Keywords: fluid dynamics; system; cns interstitial; interstitial fluid ... See more keywords
Effect of Interstitial Fluid Flow on Drug-Coated Balloon Delivery in a Patient-Specific Arterial Vessel with Heterogeneous Tissue Composition: A Simulation Study
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Engineering and Technology"
DOI: 10.1007/s13239-018-0345-2
Abstract: Angioplasty with drug-coated balloons (DCBs) using excipients as drug carriers is emerging as a potentially viable strategy demonstrating clinical efficacy and proposing additional compliance for the treatment of obstructive vascular diseases. An attempt is made… read more here.
Keywords: drug; interstitial fluid; effect interstitial; tissue ... See more keywords
The predictive value of nadir neutrophil count during treatment of cervical cancer: Interactions with tumor hypoxia and interstitial fluid pressure (IFP)
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Translational Radiation Oncology"
DOI: 10.1016/j.ctro.2017.08.002
Abstract: Background and purpose Hypoxia, high interstitial fluid pressure (IFP) and immune effects have individually been shown to modulate radiotherapy (RT) response in cervical cancer. The aim of this study was to investigate the interplay between… read more here.
Keywords: interstitial fluid; treatment; cervical cancer; cancer ... See more keywords
Microstructural changes associated with osteoporosis negatively affect loading-induced fluid flow around osteocytes in cortical bone.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2017.11.011
Abstract: Loading-induced interstitial fluid flow in the microporosities of bone is critical for osteocyte mechanotransduction and for the maintenance of tissue health, enhancing convective transport in the lacunar-canalicular system. In recent studies, our group has reported… read more here.
Keywords: lacunar canalicular; loading induced; interstitial fluid; fluid flow ... See more keywords
On the characterization of interstitial fluid flow in the skeletal muscle endomysium.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2019.103504
Abstract: In this paper, the interstitial fluid flow in skeletal muscle endomysium was examined using an in-situ indentation testing in combination with theoretical modelling. The objective was to understand the transport properties of the three-dimensional and… read more here.
Keywords: skeletal muscle; flow skeletal; muscle; interstitial fluid ... See more keywords