Programmable DNA Interstrand Crosslinking by Alkene-Alkyne [2 + 2] Photocycloaddition.
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DOI: 10.1021/jacs.3c01611
Abstract: Covalent crosslinking of DNA strands provides a useful tool for medical, biochemical, and DNA nanotechnology applications. Here we present a light-induced interstrand DNA crosslinking reaction using the modified nucleoside 5-phenylethynyl-2'-deoxyuridine (PhedU). The crosslinking ability of… read more here.
Keywords: dna; alkene alkyne; programmable dna; dna interstrand ... See more keywords