Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.10.032
Abstract: DNA interstrand crosslinks (ICLs) that are repaired in non-dividing cells must be recognized independently of replication-associated DNA unwinding. Using cell-free extracts from Xenopus eggs that support neither replication nor transcription, we establish that ICLs are recognized… read more here.
Keywords: interstrand crosslinks; dna interstrand; dna; mismatch repair ... See more keywords
WRNIP1 Is Recruited to DNA Interstrand Crosslinks and Promotes Repair
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DOI: 10.1016/j.celrep.2020.107850
Abstract: Summary The Fanconi anemia (FA) pathway repairs DNA interstrand crosslinks (ICLs). Many FA proteins are recruited to ICLs in a timely fashion so that coordinated repair can occur. However, the mechanism of this process is… read more here.
Keywords: wrnip1; interstrand crosslinks; dna interstrand; fancd2 fanci ... See more keywords