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   Articles with "interval prolongation" as a keyword



QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations

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recommendations! Published in 2025 at "Journal of Pharmacokinetics and Pharmacodynamics"

DOI: 10.1007/s10928-025-10010-x

Abstract: Prolongation of the QT interval in the ECG is a critical finding that signifies an extended duration from the onset of ventricular depolarization to the end of ventricular repolarization. It can predispose patients to life-threatening… read more here.

Keywords: risk; prolongation clinical; clinical assessment; risk factors ... See more keywords

Novel analysis of ventriculoatrial interval prolongation during a narrow QRS tachycardia using a right atrial nondecremental-midseptal accessory pathway

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recommendations! Published in 2021 at "HeartRhythm Case Reports"

DOI: 10.1016/j.hrcr.2021.06.003

Abstract: Ventriculoatrial (VA) interval prolongation during an orthodromic atrioventricular (AV) reentrant tachycardia (AVRT) with appearance of a bundle branch block (BBB) ipsilateral to an AV accessory pathway (AP) is well known as Coumel’s sign. Otherwise, VA… read more here.

Keywords: accessory pathway; interval prolongation; tachycardia; ventriculoatrial interval ... See more keywords

QT prolongation in HIV-positive patients: Review article

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recommendations! Published in 2019 at "Indian Heart Journal"

DOI: 10.1016/j.ihj.2019.11.259

Abstract: Introduction Antiretrovirals have immensely increased the average life expectancy of HIV-positive patients. However, the incidence of QT interval prolongation and other arrhythmias has also increased. Methods Pubmed and Google Scholar were searched for relevant literature… read more here.

Keywords: patients review; positive patients; prolongation hiv; interval prolongation ... See more keywords
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QTc interval prolongation in Systemic Sclerosis: Correlations with clinical variables and arrhythmic risk.

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recommendations! Published in 2017 at "International journal of cardiology"

DOI: 10.1016/j.ijcard.2017.03.088

Abstract: Article history: Received 13 March 2017 Accepted 16 March 2017 rhythmias, irrespective of QTc interval duration, as well as the potential life-saving role of an ICD-based approach in SSc patientswith cardiac involvement and a high… read more here.

Keywords: qtc; qtc interval; prolongation systemic; systemic sclerosis ... See more keywords
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Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs.

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recommendations! Published in 2020 at "Journal of pharmacological sciences"

DOI: 10.1016/j.jphs.2020.02.005

Abstract: We investigated effects of isoflurane and sevoflurane on sparfloxacin-induced QT-interval prolongation in guinea pigs under the monitoring of electrocardiogram and monophasic action potential (MAP), which was compared with those of halothane or non-inhaled anesthetics ketamine/xylazine.… read more here.

Keywords: isoflurane sevoflurane; prolongation guinea; induced interval; interval prolongation ... See more keywords

Relative QT interval prolongation and electrical inhomogeneity of cardiac repolarization in childhood obesity

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recommendations! Published in 2017 at "Progress in Pediatric Cardiology"

DOI: 10.1016/j.ppedcard.2017.08.001

Abstract: Abstract Objective Studies in adults demonstrated an association of obesity with prolongation of cardiac repolarization and an increased risk of ventricular arrhythmia and sudden cardiac death. The aim of this study was to evaluate potential… read more here.

Keywords: childhood obesity; cardiac repolarization; interval prolongation; prolongation ... See more keywords

COMBINATION THERAPY WITH DOFETILIDE AND MEXILETINE FOR ATRIAL FIBRILLATION: INCREASED EFFICACY AND DECREASED QT INTERVAL PROLONGATION

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recommendations! Published in 2020 at "Journal of the American College of Cardiology"

DOI: 10.1016/s0735-1097(20)31108-6

Abstract: Dofetilide, a class III antiarrhythmic is indicated for conversion of atrial fibrillation (AF) to sinus rhythm and maintenance of sinus rhythm. Dofetilide works by blocking the repolarizing potassium currents and hence prolongs QT interval. QT… read more here.

Keywords: atrial fibrillation; combination therapy; dofetilide; interval prolongation ... See more keywords

Serum drug levels and anti-drug antibodies in the context of dose tapering by interval prolongation of adalimumab, etanercept and ustekinumab in psoriasis patients: results of the CONDOR trial

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recommendations! Published in 2022 at "Journal of Dermatological Treatment"

DOI: 10.1080/09546634.2022.2043546

Abstract: Abstract Background Biologics for psoriasis are registered in standard dosages. In patients with low disease activity, reduction of the dose by interval prolongation can prevent overtreatment, and lower risks and costs. However, fear for increased… read more here.

Keywords: anti drug; adalimumab; drug; interval prolongation ... See more keywords

QT interval prolongation in acute antipsychotic poisoning: systematic review and recommendations

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recommendations! Published in 2025 at "Clinical Toxicology"

DOI: 10.1080/15563650.2025.2554950

Abstract: Abstract Introduction Antipsychotic medications are often associated with QT interval prolongation, which can lead to ventricular dysrhythmias, including torsade de pointes. However, unstable or significant dysrhythmic events are rare. Evidence-based recommendations on the assessment and… read more here.

Keywords: cardiac monitoring; toxicology; interval prolongation; prolongation ... See more keywords

1322. Quantifying the Effects of Frequently Prescribed Antimicrobials with Perceived Potential for QT Interval Prolongation during the COVID-19 Era

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recommendations! Published in 2020 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofaa439.1504

Abstract: Background Countless diseases and medications have been implicated in the past as causing prolongation of the QT interval Their unique role through the means of quantifying the definite magnitude of relative risk they contribute during… read more here.

Keywords: risk; covid era; 1322 quantifying; interval prolongation ... See more keywords

Predictors, incidence, and prognostic significance of PR interval prolongation in patients with ST-segment elevation myocardial infarction

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recommendations! Published in 2020 at "Coronary Artery Disease"

DOI: 10.1097/mca.0000000000000908

Abstract: Object The relationship between PR interval prolongation during hospitalization and long-term prognosis in patients with acute ST-segment elevation myocardial infarction (STEMI) has not been elucidated. This study aimed to evaluate the prevalence, predictors, and outcomes… read more here.

Keywords: elevation myocardial; prolongation; interval prolongation; segment elevation ... See more keywords