Intestinal Absorption of Prenylated Isoflavones, Glyceollins, in Sprague-Dawley Rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c02475
Abstract: Although prenylated isoflavones or glyceollins elicit physiological effects more potent than those by isoflavones, the bioavailability remains unclear. The present study aimed to clarify the intestinal absorption behavior of glyceollins in Sprague-Dawley rats. Upon oral… read more here.
Keywords: absorption; isoflavones glyceollins; prenylated isoflavones; intestinal absorption ... See more keywords
Current Knowledge on Intestinal Absorption of Anthocyanins.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c08207
Abstract: Anthocyanins are flavonoid compounds that are natural color pigments occurring in various colored plants, such as berry fruits, vegetables, and grapes. With the elucidation of their various physiological effects, anthocyanins have been identified as promising… read more here.
Keywords: chemistry; intestinal absorption; current knowledge; absorption anthocyanins ... See more keywords
Artificial Intelligence-Based Quantitative Structure–Property Relationship Model for Predicting Human Intestinal Absorption of Compounds with Serotonergic Activity
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c01117
Abstract: Oral medicines represent the largest pharmaceutical market area. To achieve a therapeutic effect, a drug must penetrate the intestinal walls, the main absorption site for orally delivered active pharmaceutical ingredients (APIs). Indeed, predicting drug absorption… read more here.
Keywords: absorption; serotonergic activity; intestinal absorption; artificial intelligence ... See more keywords
Improving intestinal absorption and antibacterial effect of florfenicol via nanocrystallisation technology
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2022.2145381
Abstract: Abstract To study the effects of nanocrystallisation technology on the intestinal absorption properties and antibacterial activity of florfenicol (FF). The florfenicol nanocrystals (FF-NC) were prepared by wet grinding and spray drying. Additionally, changes in particle… read more here.
Keywords: florfenicol; nanocrystallisation technology; intestinal absorption; absorption ... See more keywords
Niosomes for oral delivery of nateglinide: in situ–in vivo correlation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2017.1343835
Abstract: Abstract Niosomes have been claimed to enhance intestinal absorption and to widen the absorption window of acidic drugs. This was reported after monitoring the intestinal absorption in situ. Accordingly, the aim of this work was… read more here.
Keywords: absorption; oral delivery; intestinal absorption; niosomes oral ... See more keywords
Mechanisms of carotenoid intestinal absorption and the regulation of dietary lipids: lipid transporter-mediated transintestinal epithelial pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2119204
Abstract: Dietary lipids are key ingredients during cooking, processing, and seasoning of carotenoid-rich fruits and vegetables, playing vitals in affecting the absorption and utilization of carotenoids for achieving their health benefits. Besides, dietary lipids have also… read more here.
Keywords: intestinal absorption; dietary lipids; regulation; mechanisms carotenoid ... See more keywords
Improved intestinal absorption of paclitaxel by mixed micelles self-assembled from vitamin E succinate-based amphiphilic polymers and their transcellular transport mechanism and intracellular trafficking routes
Sign Up to like & getrecommendations! Published in 2018 at "Drug Delivery"
DOI: 10.1080/10717544.2017.1419513
Abstract: Abstract To ensure that antitumor drugs can be effectively transported across intestinal barrier and then quickly released in tumor cells, mixed polymeric micelles (Mix-PMs) were designed and fabricated by combining poly(2-ethyl-2-oxazoline)-vitamin E succinate (PEOz-VES) with… read more here.
Keywords: transcellular transport; intestinal absorption; mix pms;
Menthol augmented niosomes for enhanced intestinal absorption of lopinavir
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2136195
Abstract: Abstract Lopinavir is effective in treatment of HIV infection but experiences low oral bioavailability due to poor solubility, pre-systemic metabolism, and P-gp intestinal efflux. Co-processing with menthol enhanced its dissolution and intestinal permeability. Niosomes comprising… read more here.
Keywords: menthol; menthol containing; lopinavir; intestinal absorption ... See more keywords
Intestinal absorption of vitamin D: a systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Nutrition Reviews"
DOI: 10.1093/nutrit/nux034
Abstract: Context Vitamin D is frequently prescribed as a supplement, yet its absorption remains poorly understood. Objective This systematic review was performed to evaluate data on mechanisms involved in the intestinal absorption of vitamin D. Data… read more here.
Keywords: absorption; absorption vitamin; intestinal absorption; systematic review ... See more keywords
Quantitative prediction of P‐glycoprotein‐mediated drug–drug interactions and intestinal absorption using humanized mice
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15612
Abstract: P‐glycoprotein (P‐gp) exhibits a broad substrate specificity and affects pharmacokinetics, especially intestinal absorption. However, prediction, in vivo, of P‐gp‐mediated drug–drug interaction (DDI) and non‐linear absorption at the preclinical stage, is challenging. Here we evaluate the… read more here.
Keywords: absorption; intestinal absorption; mediated drug; drug ... See more keywords
Cubosomes for Enhancing Intestinal Absorption of Fexofenadine Hydrochloride: In situ and in vivo Investigation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s370235
Abstract: Purpose The aim of this work was to probe cubosomes for enhanced intestinal absorption and oral bioavailability of poorly absorbable fexofenadine HCl (FEX-HCl). Materials and Methods Two cubosomal systems were fabricated utilizing glyceryl mono-oleate, a… read more here.
Keywords: enhancing intestinal; absorption; fex hcl; intestinal absorption ... See more keywords