Lactobacillus Salivarius-Derived Indole-3-Acetic Acid Promotes AHR-PARP1 Axis-Mediated DNA Repair to Mitigate Intestinal Aging.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202515794
Abstract: Increasing evidence suggests that the aryl hydrocarbon receptor (AHR) and poly (ADP‐ribose) polymerase 1 (PARP1) are closely linked to aging and aging‐related disorders. However, the underlying mechanisms of AHR‐PARP1 axis‐mediated DNA repair in countering aging… read more here.
Keywords: intestinal aging; mediated dna; dna repair; axis mediated ... See more keywords
Intestinal aging is alleviated by uridine via regulating inflammation and oxidative stress in vivo and in vitro
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DOI: 10.1080/15384101.2022.2055252
Abstract: ABSTRACT Many countries in the world are stepping into the aging society with the challenge of the increasing agin gpopulation. The physiological functions of the human body begins to decline with aging, and the intestinal… read more here.
Keywords: vivo; intestinal aging; oxidative stress; vivo vitro ... See more keywords
Ginsenoside Rb1 improves intestinal aging via regulating the expression of sirtuins in the intestinal epithelium and modulating the gut microbiota of mice
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DOI: 10.3389/fphar.2022.991597
Abstract: Intestinal aging seriously affects the absorption of nutrients of the aged people. Ginsenoside Rb1 (GRb1) which has multiple functions on treating gastrointestinal disorders is one of the important ingredients from Ginseng, the famous herb in… read more here.
Keywords: intestinal aging; gut microbiota; expression; grb1 ... See more keywords