Comparative studies on the interaction between biogenic polyamines and bovine intestinal alkaline phosphatases: spectroscopic and theoretical approaches
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Physics"
DOI: 10.1007/s10867-018-9517-4
Abstract: In this work, the effect of two organic polyamines (spermine and spermidine) on the fluorescence intensity and activity of bovine intestinal alkaline phosphatase (BIALP) are investigated. The interaction of BIALP with spermine and spermidine was… read more here.
Keywords: comparative studies; bialp; bovine intestinal; intestinal alkaline ... See more keywords
Point-of-Care Monitoring of Colitis Using Intestinal Alkaline Phosphatase in Inflammatory Bowel Disease.
Sign Up to like & getrecommendations! Published in 2021 at "ACS sensors"
DOI: 10.1021/acssensors.0c02177
Abstract: Intestinal Alkaline Phosphatase (IAP) was investigated as a potential biomarker to monitor colitis in a mouse model of Inflammatory Bowel Disease (IBD). We developed a Point-Of-Care (POC) assay to detect IAP with a glucose meter… read more here.
Keywords: bowel disease; iap; inflammatory bowel; colitis ... See more keywords
Recent advances in intestinal alkaline phosphatase, inflammation, and nutrition.
Sign Up to like & getrecommendations! Published in 2019 at "Nutrition reviews"
DOI: 10.1093/nutrit/nuz015
Abstract: In recent years, much new data on intestinal alkaline phosphatase (IAP) have been published, and major breakthroughs have been disclosed. The aim of the present review is to critically analyze the publications released over the… read more here.
Keywords: intestinal alkaline; phosphatase; alkaline phosphatase; inflammation nutrition ... See more keywords
Intestinal alkaline phosphatase at the crossroad of intestinal health and disease – a putative role in type 1 diabetes
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DOI: 10.1111/joim.12607
Abstract: Patients with type 1 diabetes have shown an increase in circulating cytokines, altered lipoprotein metabolism and signs of vascular dysfunction in response to high‐fat meals. Intestinal alkaline phosphatase (IAP) regulates lipid transport and inflammatory responses… read more here.
Keywords: crossroad intestinal; phosphatase crossroad; type diabetes; intestinal alkaline ... See more keywords
Variant in C-terminal region of intestinal alkaline phosphatase associated with benign familial hyperphosphatasaemia
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DOI: 10.1136/jmedgenet-2017-104964
Abstract: Background A genetic diagnosis has been rarely performed in benign familial hyperphosphatasaemia, and molecular mechanism largely remains unclear. Objectives We encountered a case with benign familial hyperphosphatasaemia of intestinal alkaline phosphatase (IAP). To elucidate the… read more here.
Keywords: benign familial; iap; familial hyperphosphatasaemia; intestinal alkaline ... See more keywords
Intestinal alkaline phosphatase (IAP, IAP Enhancer) attenuates intestinal inflammation and alleviates insulin resistance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.927272
Abstract: In this study, we investigated the effects of intestinal alkaline phosphatase (IAP) in controlled intestinal inflammation and alleviated associated insulin resistance (IR). We also explored the possible underlying molecular mechanisms, showed the preventive effect of… read more here.
Keywords: inflammation; iap iap; alkaline phosphatase; iap ... See more keywords
A role for intestinal alkaline phosphatase in preventing liver fibrosis
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DOI: 10.7150/thno.48468
Abstract: Rationale: Liver fibrosis is frequently associated with gut barrier dysfunction, and the lipopolysaccharides (LPS) -TLR4 pathway is common to the development of both. Intestinal alkaline phosphatase (IAP) has the ability to detoxify LPS, as well… read more here.
Keywords: fibrosis; iap; liver fibrosis; intestinal alkaline ... See more keywords