Impact of intestinal dysbiosis-related drugs on the efficacy of immune checkpoint inhibitors in clinical practice
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-020-02315-9
Abstract: Purpose Intestinal dysbiosis has emerged as a biomarker of response to immune checkpoint inhibitors (ICIs). It can be caused by antibiotics, although it may also result from the use of other drugs that have been… read more here.
Keywords: intestinal dysbiosis; immune checkpoint; dysbiosis related; dysbiosis ... See more keywords
Intestinal dysbiosis promotes epithelial-mesenchymal transition by activating tumor-associated macrophages in ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "Pathogens and Disease"
DOI: 10.1093/femspd/ftz019
Abstract: We aimed to investigate the relationship of intestinal dysbiosis (IDB) and ovarian cancer progression, and understand its underlying signaling mechanisms. IDB was induced with high dose antibiotics. The xenograft mouse model was used to assess… read more here.
Keywords: intestinal dysbiosis; mesenchymal transition; epithelial mesenchymal; ovarian cancer ... See more keywords
Intestinal Dysbiosis Correlates With Sirolimus-Induced Metabolic Disorders in Mice.
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/tp.0000000000003494
Abstract: BACKGROUND Long-time use of pharmacological immunosuppressive agents frequently leads to metabolic disorders. Most studies have focused on islet toxicity leading to post-transplantation diabetes mellitus. In contrast, the link between intestinal dysbiosis and immunosuppressive drug-induced metabolic… read more here.
Keywords: sirolimus induced; systemic inflammation; metabolic disorders; induced metabolic ... See more keywords
Hyperoxia combined with the B‐cell antagonist rituximab led to intestinal dysbiosis in neonatal mice
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12984
Abstract: The adverse factors impacting the intestinal microbiota of newborns remain to be elucidated. We put forward a hypothesis that hyperoxia in combination with rituximab exhibits a synergistic effect that interferes with neonatal intestinal microbiota. Six… read more here.
Keywords: intestinal microbiota; dysbiosis; intestinal dysbiosis; hyperoxia ... See more keywords
AB0155 INTESTINAL MICROBIAL SIGNATURE IN ANKYLOSING SPONDYLITIS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.5903
Abstract: Background: Intestinal microbiota analysis is a current subject because of its important role in the pathogenesis of various autoimmune diseases such as intestinal inflammatory diseases or spondyloarthritis. Objectives: The objective of this paper was to… read more here.
Keywords: dysbiosis; intestinal dysbiosis; microbiota; ankylosing spondylitis ... See more keywords
Neonatal intestinal dysbiosis in necrotizing enterocolitis
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine"
DOI: 10.1186/s10020-018-0002-0
Abstract: Necrotizing Enterocolitis (NEC) is one of the most devastating gastrointestinal diseases in neonates, particularly among preterm infants in whom surgical NEC is the leading cause of morbidity. NEC pathophysiology occurs in the hyper-reactive milieu of… read more here.
Keywords: intestinal dysbiosis; medicine; dysbiosis necrotizing; necrotizing enterocolitis ... See more keywords
Intestinal dysbiosis and probiotic use: its place in hepatic encephalopathy in cirrhosis
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Gastroenterology"
DOI: 10.20524/aog.2023.0776
Abstract: The gut microbiota, which plays an important role in health and disease processes, is affected by many disease processes, such as cirrhosis, and dysbiosis can lead to the development of numerous liver diseases, including complications… read more here.
Keywords: hepatic encephalopathy; dysbiosis; treatment; cirrhosis ... See more keywords
Is Intestinal Dysbiosis-Associated With Immunosuppressive Therapy a Key Factor in the Pathophysiology of Post-Transplant Diabetes Mellitus?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.898878
Abstract: Post-transplant diabetes mellitus (PTDM) is one of the most common and deleterious comorbidities after solid organ transplantation (SOT). Its incidence varies depending on the organs transplanted and can affect up to 40% of patients. Current… read more here.
Keywords: transplant diabetes; dysbiosis; post transplant; diabetes mellitus ... See more keywords
Intestinal Dysbiosis Is Associated with Altered Short-Chain Fatty Acids and Serum-Free Fatty Acids in Systemic Lupus Erythematosus
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00023
Abstract: Metabolic impairments are a frequent hallmark of systemic lupus erythematosus (SLE). Increased serum levels of free fatty acids (FFA) are commonly found in these patients, although the underlying causes remain elusive. Recently, it has been… read more here.
Keywords: intestinal dysbiosis; fatty acids; lupus patients; ffa ... See more keywords
Intestinal Dysbiosis in Autoimmune Diabetes Is Correlated With Poor Glycemic Control and Increased Interleukin-6: A Pilot Study
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01689
Abstract: Intestinal dysbiosis associated with immunological deregulation, leaky gut, bacterial translocation, and systemic inflammation has been associated with autoimmune diseases, such as type 1 diabetes (T1D). The aim of this study was to investigate the intestinal… read more here.
Keywords: intestinal dysbiosis; dysbiosis; study; t1d patients ... See more keywords
Detection of Intestinal Dysbiosis in Post-COVID-19 Patients One to Eight Months after Acute Disease Resolution
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191610189
Abstract: The intestinal microbiota plays an important role in the immune response against viral infections, modulating both innate and adaptive immune responses. The cytokine storm is associated with COVID-19 severity, and the patient’s immune status is… read more here.
Keywords: post; intestinal dysbiosis; post covid; covid patients ... See more keywords