Rhodococcus spp. interacts with human norovirus in clinical samples and impairs its replication on human intestinal enteroids
Sign Up to like & getrecommendations! Published in 2025 at "Gut Microbes"
DOI: 10.1080/19490976.2025.2469716
Abstract: ABSTRACT Viral infections, particularly human norovirus (NoV), are a leading cause of diarrheal diseases globally. To better understand NoV susceptibility, it is crucial to investigate both host glycobiology and the influence of the microbiota. Histo-blood… read more here.
Keywords: human norovirus; rhodococcus; human intestinal; gii ... See more keywords
Human Sapovirus Replication in Human Intestinal Enteroids
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DOI: 10.1128/jvi.00383-23
Abstract: Human sapoviruses (HuSaVs) are a frequent but overlooked cause of acute gastroenteritis, especially in children. Little is known about this pathogen, whose successful in vitro cultivation was reported only recently, in a cancer cell-derived line.… read more here.
Keywords: husav; human sapoviruses; replication; intestinal enteroids ... See more keywords
Human Norovirus Efficiently Replicates in Differentiated 3D-Human Intestinal Enteroids
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DOI: 10.1128/jvi.00855-22
Abstract: The human norovirus (HNoV) clinical and socio-economic impact calls for immediate action in the development of anti-infectives. Physiologically relevant in vitro models are hence needed to study HNoV biology, tropism, and mechanisms of viral-associated disease,… read more here.
Keywords: hnov; infection; biology; intestinal enteroids ... See more keywords
Infant and adult human intestinal enteroids are morphologically and functionally distinct
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DOI: 10.1128/mbio.01316-24
Abstract: ABSTRACT Human intestinal enteroids (HIEs) are gaining recognition as physiologically relevant models of the intestinal epithelium. While HIEs from adults are used extensively in biomedical research, few studies have used HIEs from infants. Considering the… read more here.
Keywords: epithelium; adult; physiology; human intestinal ... See more keywords
Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater
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DOI: 10.3201/eid2807.220219
Abstract: Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such… read more here.
Keywords: persistence; norovirus; seawater; intestinal enteroids ... See more keywords
Human Intestinal Enteroids Model MHC-II in the Gut Epithelium
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DOI: 10.3389/fimmu.2019.01970
Abstract: The role of intestinal epithelial cells (IECs) in mucosal tolerance and immunity remains poorly understood. We present a method for inducing MHC class II (MHC-II) in human enteroids, “mini-guts” derived from small intestinal crypt stem… read more here.
Keywords: mhc gut; mhc; enteroids model; model mhc ... See more keywords