Human Sapovirus Replication in Human Intestinal Enteroids
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00383-23
Abstract: Human sapoviruses (HuSaVs) are a frequent but overlooked cause of acute gastroenteritis, especially in children. Little is known about this pathogen, whose successful in vitro cultivation was reported only recently, in a cancer cell-derived line.… read more here.
Keywords: husav; human sapoviruses; replication; intestinal enteroids ... See more keywords
Human Norovirus Efficiently Replicates in Differentiated 3D-Human Intestinal Enteroids
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00855-22
Abstract: The human norovirus (HNoV) clinical and socio-economic impact calls for immediate action in the development of anti-infectives. Physiologically relevant in vitro models are hence needed to study HNoV biology, tropism, and mechanisms of viral-associated disease,… read more here.
Keywords: hnov; infection; biology; intestinal enteroids ... See more keywords
Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater
Sign Up to like & getrecommendations! Published in 2022 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2807.220219
Abstract: Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such… read more here.
Keywords: persistence; norovirus; seawater; intestinal enteroids ... See more keywords
Human Intestinal Enteroids Model MHC-II in the Gut Epithelium
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01970
Abstract: The role of intestinal epithelial cells (IECs) in mucosal tolerance and immunity remains poorly understood. We present a method for inducing MHC class II (MHC-II) in human enteroids, “mini-guts” derived from small intestinal crypt stem… read more here.
Keywords: mhc gut; mhc; enteroids model; model mhc ... See more keywords