Galectin-4 as a Novel Biomarker of Neonatal Intestinal Injury
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-06929-z
Abstract: Neonates are at risk of gastrointestinal emergencies including necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP). Identifying biomarkers to aid in diagnosis is imperative. We hypothesized that circulating intestinal-specific protein concentrations would distinguish infants with… read more here.
Keywords: biomarker neonatal; intestinal specific; intestinal injury; control infants ... See more keywords
Human β-Defensin 118 Attenuates Escherichia coli K88–Induced Inflammation and Intestinal Injury in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-020-09725-9
Abstract: Antibiotics are widely used to treat various inflammatory bowel diseases caused by enterotoxigenic Escherichia coli (ETEC). However, continuous use of antibiotics may lead to drug resistance. In this study, we investigated the role of human… read more here.
Keywords: inflammation intestinal; induced inflammation; escherichia coli; defensin 118 ... See more keywords
Role of TLR5 in inflammation and tissue damage after intestinal ischemia-reperfusion injury.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.08.083
Abstract: BACKGROUND Intestinal ischemia/reperfusion (I/R) injury is a life-threatening complication that leads to inflammation and remote organ damage. However, the underlying mechanism is not yet fully understood. Toll-like receptor 5 (TLR5) is highly expressed in mucosa… read more here.
Keywords: role tlr5; inflammation; intestinal injury; damage ... See more keywords
Amelioration of whole abdominal irradiation‐induced intestinal injury in mice with 3,3′‐Diindolylmethane (DIM)
Sign Up to like & getrecommendations! Published in 2019 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.410
Abstract: ABSTRACT Ionizing radiation‐induced intestinal injury is a catastrophic disease with limited effective therapies. 3,3′‐Diindolylmethane (DIM), a potent antioxidant agent, has previously been shown to ameliorate hematopoietic injury in a murine model of total body radiation… read more here.
Keywords: irradiation; induced intestinal; intestinal injury; dim ... See more keywords
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.04.182
Abstract: We previously obtained and characterized a novel sulfated derivative of the exopolysaccharides from Enterobacter cloacae Z0206 (SEPS). This study aimed at investigating the effects and mechanism of SEPS against dextran sulfate sodium (DSS) induced intestinal… read more here.
Keywords: induced intestinal; dss induced; intestinal injury; enterobacter cloacae ... See more keywords
Effects of endothelin receptor blockade and COX inhibition on intestinal I/R injury in a rat model: Experimental research.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of surgery"
DOI: 10.1016/j.ijsu.2020.08.061
Abstract: BACKGROUND Intestinal ischemia is a highly morbid and mortal condition with no specific treatment. The present study aimed to investigate the effects of cyclooxygenase (COX) inhibition synchronized with nitric oxide (NO) release and endothelin (ET)… read more here.
Keywords: receptor blockade; treatment; endothelin receptor; intestinal injury ... See more keywords
Eugenol Alleviates TGEV-Induced Intestinal Injury via Suppressing ROS/NLRP3/GSDMD-Dependent Pyroptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c05833
Abstract: Transmissible gastroenteritis virus (TGEV), a coronavirus, is one of the main causative agents of diarrhea in piglets and significantly impacts the global swine industry. Pyroptosis is involved in the pathogenesis of coronavirus, but its role… read more here.
Keywords: induced intestinal; pyroptosis; tgev induced; eugenol ... See more keywords
N-(1-carbamoyl-2-phenylethyl) butyramide reduces antibiotic-induced intestinal injury, innate immune activation and modulates microbiota composition
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41295-x
Abstract: The use/misuse of antibiotics leads to pathological features referring to antibiotic-induced intestinal injury (AIJ), a clinical issue that plays a prominent role in the development of severe digestive disturbances. AIJ is characterized by loss of… read more here.
Keywords: induced intestinal; carbamoyl phenylethyl; intestinal injury; antibiotic induced ... See more keywords
C/EBPδ protects from radiation-induced intestinal injury and sepsis by suppression of inflammatory and nitrosative stress
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-49437-x
Abstract: Ionizing radiation (IR)-induced intestinal damage is characterized by a loss of intestinal crypt cells, intestinal barrier disruption and translocation of intestinal microflora resulting in sepsis-mediated lethality. We have shown that mice lacking C/EBPδ display IR-induced… read more here.
Keywords: sepsis; nitrosative stress; induced intestinal; intestinal injury ... See more keywords
Corrigendum: Protective effects of ginsenoside Rg1 on intestinal ischemia/reperfusion injury-induced oxidative stress and apoptosis via activation of the Wnt/β-catenin pathway
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45252
Abstract: Ginsenoside Rg1 (Rg1) is one of the major bioactive ingredients in Panax ginseng, and it attenuates inflammation and apoptosis. The aims of our study were to explore the potential of Rg1 for the treatment of… read more here.
Keywords: rg1; apoptosis; intestinal injury; injury ... See more keywords
Dopamine-derived nanoparticles for the protection of irradiation-induced intestinal injury by maintaining intestinal homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d1bm02026a
Abstract: Radiotherapy of abdominal and pelvic tumors almost inevitably injures the intestine by oxidative stress and causes inflammation. Regrettably, traditional radioprotective agents for irradiation (IR) induced intestinal injury suffer from challenges such as poor solubility, unsatisfactory… read more here.
Keywords: induced intestinal; irradiation induced; injury; intestinal injury ... See more keywords