Critical Role for a Subset of Intestinal Macrophages in Shaping Gut Microbiota in Adult Zebrafish.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.09.025
Abstract: The gut microbiota is strongly influenced by environmental factors, although host contribution is far less understood. We leveraged macrophage-deficient interferon regulatory factor irf8 zebrafish mutants to investigate the role of macrophages in this process. In… read more here.
Keywords: adult; gut; intestinal macrophages; gut microbiota ... See more keywords
Origin, Differentiation, and Function of Intestinal Macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02733
Abstract: Macrophages are increasingly recognized as essential players in the maintenance of intestinal homeostasis and as key sentinels of the intestinal immune system. However, somewhat paradoxically, they are also implicated in chronic pathologies of the gastrointestinal… read more here.
Keywords: origin differentiation; differentiation function; intestinal macrophages; function intestinal ... See more keywords
A potential therapeutic target in traditional Chinese medicine for ulcerative colitis: Macrophage polarization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.999179
Abstract: Intestinal macrophages are the main participants of intestinal immune homeostasis and intestinal inflammation. Under different environmental stimuli, intestinal macrophages can be polarized into classical activated pro-inflammatory phenotype (M1) and alternative activated anti-inflammatory phenotype (M2). Its… read more here.
Keywords: macrophage polarization; intestinal macrophages; chinese medicine; polarization ... See more keywords