Cutaneous Intestinal Metaplasia With Adenocarcinoma Treated With Intralesional Fluorouracil.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4842
Abstract: This case report describes a patient with cutaneous intestinal metaplasia with invasive adenocarcinoma treated successfully with intralesional fluorouracil. read more here.
Keywords: intestinal metaplasia; intralesional fluorouracil; cutaneous intestinal; adenocarcinoma treated ... See more keywords
High-risk individuals for gastric cancer would be missed for surveillance without subtyping of intestinal metaplasia
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03116-3
Abstract: The use of Operative Link on Gastritis Assessment (OLGA) and Operative Link on Gastritis Assessment based on Intestinal Metaplasia (OLGIM) staging system is recommended for identifying subjects at risk for developing gastric cancer; usually high-risk… read more here.
Keywords: gastric cancer; high risk; risk; intestinal metaplasia ... See more keywords
CDX-2 Expression in Esophageal Biopsies Without Goblet Cell Intestinal Metaplasia May Be Predictive of Barrett’s Esophagus
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05914-x
Abstract: Background CDX-2 is a nuclear homeobox transcription factor not normally expressed in esophageal and gastric epithelia, reported to highlight intestinal metaplasia (IM) in the esophagus. Pathological absence of goblet cells at initial screening via hematoxylin… read more here.
Keywords: intestinal metaplasia; barrett esophagus; goblet; cdx ... See more keywords
Deoxycholic acid-stimulated macrophage-derived exosomes promote intestinal metaplasia and suppress proliferation in human gastric epithelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173566
Abstract: The crosstalk between macrophages and gastric epithelial cells has emerged as a player in chronic inflammation during intestinal metaplasia. However, the role of bile acid on this modulation remains to be studied. We hypothesized that… read more here.
Keywords: gastric epithelial; intestinal metaplasia; epithelial cells; metaplasia ... See more keywords
TGR5-HNF4α axis contributes to bile acid-induced gastric intestinal metaplasia markers expression
Sign Up to like & getrecommendations! Published in 2020 at "Cell Death Discovery"
DOI: 10.1038/s41420-020-0290-3
Abstract: Intestinal metaplasia (IM) increases the risk of gastric cancer. Our previous results indicated that bile acids (BAs) reflux promotes gastric IM development through kruppel-like factor 4 (KLF4) and caudal-type homeobox 2 (CDX2) activation. However, the… read more here.
Keywords: intestinal metaplasia; hnf4 axis; hnf4; acid ... See more keywords
Linked color imaging-based endoscopic grading of gastric intestinal metaplasia and histological gastritis staging in the assessment of gastric cancer risk
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2022.2085061
Abstract: Abstract Objective To evaluate the value and compare the effectiveness of linked color imaging-based endoscopic grading of gastric intestinal metaplasia (LCI-EGGIM) and operative link on gastric intestinal metaplasia (OLGIM) in risk stratification of early gastric… read more here.
Keywords: gastric intestinal; egc; risk; lci eggim ... See more keywords
Caudal type homeoboxes as a driving force in Helicobacter pylori infection-induced gastric intestinal metaplasia
Sign Up to like & getrecommendations! Published in 2020 at "Gut Microbes"
DOI: 10.1080/19490976.2020.1809331
Abstract: ABSTRACT Helicobacter pylori (H. pylori), a common pathogenic bacterium in the stomach, has been demonstrated to be a major cause of gastric cancer (GC). The typical pathological evolution of H. pylori infection-induced GC involves development… read more here.
Keywords: intestinal metaplasia; infection; pylori infection; type ... See more keywords
Deoxycholic acid induces gastric intestinal metaplasia by activating STAT3 signaling and disturbing gastric bile acids metabolism and microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2120744
Abstract: ABSTRACT Intestinal metaplasia (IM) is the inevitable precancerous stage to develop intestinal-type gastric cancer (GC). Deoxycholic acid (DCA) is the main bile acid (BA) component of duodenogastric reflux and has shown an increased concentration during… read more here.
Keywords: metabolism; ins gas; deoxycholic acid; dca ... See more keywords
Guilt by association: intestinal metaplasia does not progress to gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Gastroenterology"
DOI: 10.1097/mog.0000000000000472
Abstract: Purpose of review This review integrates the new thinking about relationships between gastric cancer and intestinal metaplasia/pseudopyloric metaplasia (SPEM). We address whether recent studies have closed or widened the knowledge gap regarding gastric cancer pathogenesis… read more here.
Keywords: intestinal metaplasia; metaplasia; guilt association; gastric cancer ... See more keywords
Diagnosis: gastric intestinal metaplasia: what to do next?
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Gastroenterology"
DOI: 10.1097/mog.0000000000000576
Abstract: PURPOSE OF REVIEW One of the most vexing problems for gastroenterologists is what actions to take after receiving a histological diagnosis of gastric intestinal metaplasia. We approach the problem by starting with suggesting a biopsy… read more here.
Keywords: metaplasia; intestinal metaplasia; gastric intestinal; diagnosis gastric ... See more keywords
Intestinal Metaplasia of the Esophagus in Children With Esophageal Atresia
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DOI: 10.1097/mpg.0000000000001558
Abstract: Objectives: Patients with esophageal atresia/tracheoesophageal fistula (EA-TEF) can develop Barrett esophagus as a long-term consequence of their condition. Intestinal metaplasia (IM), a risk factor for developing adenocarcinoma of the esophagus, has not been well characterized… read more here.
Keywords: intestinal metaplasia; metaplasia esophagus; metaplasia; diagnosis ... See more keywords