Probiotic‐derived nanoparticles inhibit ALD through intestinal miR194 suppression and subsequent FXR activation
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DOI: 10.1002/hep.32608
Abstract: Background and Aims: Intestinal farnesoid X receptor (FXR) plays a critical role in alcohol‐associated liver disease (ALD). We aimed to investigate whether alcohol‐induced dysbiosis increased intestinal microRNA194 (miR194) that suppressed Fxr transcription and whether Lactobacillus… read more here.
Keywords: intestinal mir194; alcohol; mir194; fxr activation ... See more keywords