A collagen hydrogel-based intestinal model enabling physiological epithelial-immune cell interactions in host-microbe studies.
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DOI: 10.1039/d5bm00612k
Abstract: The human intestine orchestrates complex immune responses to external stimuli, including trillions of gut microbes. Understanding host-microbiota interactions remains challenging due to the complex cellular composition of intestinal tissues. In this study, we present InTRIC… read more here.
Keywords: intestinal model; epithelial immune; model; immune ... See more keywords
Development of a novel in vitro 3D intestinal model for permeability evaluations
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Food Sciences and Nutrition"
DOI: 10.1080/09637486.2019.1700940
Abstract: Abstract In this work, a new three-dimensional (3D) in vitro cell model was described, which was comprised of an epithelium, a subepithelial fibroblast network and an extracellular matrix, thereby more closely mimicking the morphology of… read more here.
Keywords: intestinal model; novel vitro; vitro intestinal; permeability ... See more keywords
Bacteria enable tolerance to bile salt exposure in an immune-competent human intestinal model.
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DOI: 10.1080/19490976.2025.2514144
Abstract: ABSTRACT Bile salts (BS) are known to be highly important in modulating bacteria-host crosstalk in the gut, serving as essential signaling molecules governing intestinal homeostasis. However, understanding of this crosstalk is limited by challenges of… read more here.
Keywords: competent human; bile; immune competent; intestinal model ... See more keywords
Insights into amebiasis using a human 3D‐intestinal model
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DOI: 10.1111/cmi.13203
Abstract: Entamoeba histolytica is the causative agent of amebiasis, an infectious disease targeting the intestine and the liver in humans. Two types of intestinal infection are caused by this parasite: silent infection, which occurs in the… read more here.
Keywords: intestinal model; using human; model; amebiasis using ... See more keywords
Human milk inhibits some enveloped virus infections, including SARS-CoV-2, in an intestinal model
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DOI: 10.26508/lsa.202201432
Abstract: Human milk blocks some enveloped, but not non-enveloped, virus infections in a primary human fetal intestinal model and the transcriptomic data points towards inhibition of entry mediated by ATP1A1. Human milk is important for antimicrobial… read more here.
Keywords: human milk; virus infections; milk; intestinal model ... See more keywords