Abnormalities in metabolic pathways in celiac disease investigated by the metabolic profiling of small intestinal mucosa, blood plasma and urine by NMR spectroscopy
Sign Up to like & getrecommendations! Published in 2020 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4305
Abstract: Celiac disease (CeD) is an autoimmune enteropathy caused by gluten intake in genetically predisposed individuals. We investigated the metabolism of CeD by metabolic profiling of intestinal mucosa, blood plasma and urine using NMR spectroscopy and… read more here.
Keywords: plasma urine; intestinal mucosa; spectroscopy; mucosa blood ... See more keywords
Minimal Lesions of the Small Intestinal Mucosa: More than Morphology
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DOI: 10.1007/s10620-020-06571-1
Abstract: Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of… read more here.
Keywords: minimal lesions; small intestinal; diagnosis; intestinal mucosa ... See more keywords
Use of a combination of in vitro models to investigate the impact of chlorpyrifos and inulin on the intestinal microbiota and the permeability of the intestinal mucosa
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-018-2332-4
Abstract: Dietary exposure to the organophosphorothionate pesticide chlorpyrifos (CPF) has been linked to dysbiosis of the gut microbiota. We therefore sought to investigate whether (i) CPF’s impact extends to the intestinal barrier and (ii) the prebiotic… read more here.
Keywords: intestinal mucosa; inulin; vitro models; microbiota ... See more keywords
Synthesis of thiolated, PEGylated and POZylated silica nanoparticles and evaluation of their retention on rat intestinal mucosa in vitro
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.06.032
Abstract: &NA; In this study, we synthesised thiolated silica nanoparticles using 3‐mercaptopropyltrimethoxysilane and functionalised them with either 5 kDa methoxy polyethylene glycol maleimide (PEG) or 5 kDa alkyne‐terminated poly(2‐ethyl‐2‐oxazoline) (POZ). The main objectives of this study… read more here.
Keywords: intestinal mucosa; rat intestinal; silica nanoparticles; pozylated nanoparticles ... See more keywords
MicroRNA-125a suppresses intestinal mucosal inflammation through targeting ETS-1 in patients with inflammatory bowel diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2019.04.014
Abstract: MicroRNA (miR)-125a is highly expressed in T cells and regulates the functions of Treg through the IL-6-STAT3 signaling pathway. However, the role of miR-125a in regulating immune responses in intestinal mucosa of patients with inflammatory… read more here.
Keywords: patients inflammatory; inflammatory bowel; intestinal mucosa; bowel diseases ... See more keywords
First Degree Relatives of Patients with Celiac Disease Harbour an Intestinal Transcriptomic Signature that Might Protect them from Enterocyte Damage
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Translational Gastroenterology"
DOI: 10.1038/s41424-018-0059-7
Abstract: Introduction: Celiac disease (CeD) is an autoimmune enteropathy which affects approximately 0.7% of the global population. While first‐degree relatives (FDR) of patients with CeD have a 7.5% risk of developing enteropathy, many remain protected. Therefore,… read more here.
Keywords: degree relatives; first degree; fdr; intestinal mucosa ... See more keywords
The role of γδ T cells in the interaction between commensal and pathogenic bacteria in the intestinal mucosa.
Sign Up to like & getrecommendations! Published in 2022 at "International reviews of immunology"
DOI: 10.1080/08830185.2022.2076846
Abstract: The intestinal mucosa is an important structure involved in resistance to pathogen infection. It is mainly composed of four barriers, which have different but interrelated functions. Pathogenic bacteria can damage these intestinal mucosal barriers. Here,… read more here.
Keywords: pathogenic bacteria; cells interaction; commensal bacteria; role cells ... See more keywords
Dietary nutrients shape gut microbes and intestinal mucosa via epigenetic modifications.
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DOI: 10.1080/10408398.2020.1828813
Abstract: The imbalance of intestinal microecology firstly impairs intestinal mucosa barrier and function, then further damages the functions and homeostasis of distal organs, leading to systemic diseases. Nutrients, transplantation of bacteria flora and modes of life… read more here.
Keywords: intestinal mucosa; dietary nutrients; epigenetic modifications; shape gut ... See more keywords
Microbial contribution to the caloric restriction-triggered regulation of the intestinal levels of glutathione transferases, taurine, and bile acid
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DOI: 10.1080/19490976.2021.1992236
Abstract: ABSTRACT Recently we showed that caloric restriction (CR) triggers an increase in the levels of free taurine, taurine-conjugated bile acids (BA), and other taurine conjugates in intestinal mucosa while decreasing glutathione (GSH) levels in wild-type… read more here.
Keywords: intestinal mucosa; taurine conjugates; caloric restriction; microbial contribution ... See more keywords
Surprising absence of heparin in the intestinal mucosa of baby pigs
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DOI: 10.1093/glycob/cww104
Abstract: Heparin, a member of a family of molecules called glycosaminoglycans, is biosynthesized in mucosal mast cells. This important anticoagulant polysaccharide is primarily produced by extraction of the mast cell-rich intestinal mucosa of hogs. There is… read more here.
Keywords: intestinal mucosa; mast cells; mast; baby pigs ... See more keywords
Acesulfame-K induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of gastroenterology and hepatology"
DOI: 10.1111/jgh.15654
Abstract: BACKGROUND AND AIMS The artificial sweetener acesulfame potassium (ACK) is officially approved as safe for intake and has been used in processed foods. However, ACKs have been reported to induce metabolic syndrome, along with alteration… read more here.
Keywords: intestinal mucosa; ack; lymphocyte migration; migration ... See more keywords