Effect of a chamomile extract in protecting against radiation‐induced intestinal mucositis
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6263
Abstract: Compounds that prevent radiation‐induced mucositis may offer new therapeutic strategies for maintaining intestinal integrity in patients undergoing radiotherapy. A specially formulated chamomile extract was studied with the hope of proving efficacy in this regard. Intestinal… read more here.
Keywords: mucositis; intestinal mucositis; radiation induced; chamomile extract ... See more keywords
Role of regulatory T cells in irinotecan‐induced intestinal mucositis
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.01.006
Abstract: Abstract Intestinal mucositis (IM) is a common side effect of irinotecan‐based chemotherapy. The involvement of inflammatory mediators, such as TNF‐&agr;, IL1‐&bgr;, IL‐18 and IL‐33, has been demonstrated. However, the role of adaptive immune system cells,… read more here.
Keywords: irinotecan induced; intestinal mucositis; regulatory cells; role ... See more keywords
Anti-inflammatory effects of Radix aucklandiae herbal preparation ameliorate intestinal mucositis induced by 5-fluorouracil in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.113912
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE 5-Fluorouracil (5-FU) is a chemotherapy agent that is widely used in clinical oncologic practice. However, intestinal mucositis is the most frequently occurring side effect of cancer therapy with 5-FU. Based on a literature… read more here.
Keywords: mucositis; intestinal mucositis; herbal preparation; aucklandiae herbal ... See more keywords
Paraprobiotic Enterococcus faecalis EC-12 prevents the development of irinotecan-induced intestinal mucositis in mice.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120445
Abstract: AIMS This study tested the protective effect of purified paraprobiotic Enterococcus faecalis (EC-12) and an E. faecalis-based formulation (Med LanS) on irinotecan-induced intestinal mucositis murine model. MAIN METHODS C57BL/6 male mice received saline, irinotecan (75 mg/Kg,… read more here.
Keywords: mucositis; paraprobiotic enterococcus; faecalis; intestinal mucositis ... See more keywords
Selenium Administration Attenuates 5-Flurouracil-Induced Intestinal Mucositis
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DOI: 10.1080/01635581.2017.1300289
Abstract: ABSTRACT Chemotherapy-induced mucositis is mediated by the release of proinflammatory cytokines and reactive oxygen species. Selenium has several metabolic functions, including the protection of membrane lipids and macromolecules against oxidative damage. However, to date, there… read more here.
Keywords: chemotherapy; administration; mucositis; intestinal mucositis ... See more keywords
Armillariella Oral Solution Ameliorates Small Intestinal Damage in a Mouse Model of Chemotherapy-Induced Mucositis
Sign Up to like & getrecommendations! Published in 2019 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2019.1599029
Abstract: Abstract Background: Armillariella oral solution (AOS) shows therapeutic effect on gastrointestinal disorders. We aimed to investigate the potential efficacy of AOS on chemotherapy-induced intestinal mucositis in mice. Methods: Intestinal mucositis was induced in C57BL/6 mice… read more here.
Keywords: mucositis; armillariella oral; oral solution; intestinal mucositis ... See more keywords
Mitochondrial DNA as a Possible Ligand for TLR9 in Irinotecan-induced Small Intestinal Mucositis
Sign Up to like & getrecommendations! Published in 2022 at "Immunological Investigations"
DOI: 10.1080/08820139.2022.2026379
Abstract: ABSTRACT Cancer chemotherapy and radiotherapy may result in mucositis characterized by stem cell damage and inflammation in the gastrointestinal tract. The molecular mechanisms underlying this pathology remain unknown. Based on the assumption that mitochondrial CPG-DNA… read more here.
Keywords: dna; intestinal mucositis; pathology; irinotecan induced ... See more keywords
Luteolin prevents irinotecan‐induced intestinal mucositis in mice through antioxidant and anti‐inflammatory properties
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14987
Abstract: Intestinal mucositis refers to mucosal damage caused by cancer treatment, and irinotecan is one of the agents most associated with this condition. Focusing on the development of alternatives to prevent this important adverse effect, we… read more here.
Keywords: mucositis; irinotecan induced; prevents irinotecan; induced intestinal ... See more keywords
NOD-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome Activation Exacerbates 5-Fluorouracil-Induced Small Intestinal Mucositis via Interleukin-1β Activation
Sign Up to like & getrecommendations! Published in 2019 at "Digestion"
DOI: 10.1159/000504974
Abstract: Background and Aim: 5-Fluorouracil (5-FU) is an anticancer agent that induces intestinal mucositis, which causes diarrhea and dehydration. The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is responsible for inflammatory response activation via caspase-1… read more here.
Keywords: caspase; mucositis; small intestinal; intestinal mucositis ... See more keywords
The Superoxide Dismutase Mimetic M40403, Improves 5-Fluorouracil-induced Small Intestinal Mucositis in a Mouse Model
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DOI: 10.21873/invivo.12401
Abstract: Background/Aim: Intestinal mucositis with diarrhea is a dose-limiting toxicity of 5-fluorouracil (5-FU). M40403, a superoxide dismutase mimetic, was evaluated on whether it improves the mucositis with diarrhea. Materials and Methods: BALB/c mice were treated with… read more here.
Keywords: mucositis; microscopy; m40403; intestinal mucositis ... See more keywords
Alteration of Gut Microbiota and Inflammatory Cytokine/Chemokine Profiles in 5-Fluorouracil Induced Intestinal Mucositis
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00455
Abstract: Disturbed homeostasis of gut microbiota has been suggested to be closely associated with 5-fluorouracil (5-Fu) induced mucositis. However, current knowledge of the overall profiles of 5-Fu-disturbed gut microbiota is limited, and so far there is… read more here.
Keywords: mucositis; induced intestinal; intestinal mucositis; colon ... See more keywords