Treg and intestinal myofibroblasts-derived Amphiregulin induced by TGF-β mediates intestinal fibrosis in Crohn’s disease
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DOI: 10.1186/s12967-025-06413-6
Abstract: Intestinal fibrosis is a serious complication of Crohn’s disease (CD), often resulting from chronic inflammation. However, the precise mechanisms through which inflammation induces intestinal fibrosis remain inadequately elucidated. A comprehensive single-cell atlas of full-thickness CD,… read more here.
Keywords: fibrosis; crohn disease; intestinal myofibroblasts; human intestinal ... See more keywords