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Published in 2017 at "British Journal of Surgery"
DOI: 10.1002/bjs.10333
Abstract: In patients with small intestinal neuroendocrine tumours (SI‐NETs), serotonin and other cytokines released from tumour cells may induce fibrosis, leading to carcinoid heart disease and abdominal fibrotic reactions. The aim of this study was to… read more here.
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Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02534-8
Abstract: Small intestinal neuroendocrine tumours (siNETs) with a Ki-67 proliferation index between 3 and 20% belong to WHO grade 2. Response to treatment may be monitored by blood chromogranin A (CgA) and urine 5-hydroxyindoleacetic acid (5HIAA).… read more here.
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Published in 2021 at "Clinical Endocrinology"
DOI: 10.1111/cen.14527
Abstract: The imaging of intestinal neuroendocrine tumours (NETs) relies on functional positron emission tomography (PET) tracers; these tumours can be studied by means of both 68Ga‐DOTA peptides and 18F‐fluorodihydroxyphenyl‐ l‐alanine (18F‐DOPA) PET/computed tomography (CT). As yet,… read more here.
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Published in 2019 at "Histopathology"
DOI: 10.1111/his.13771
Abstract: Well‐differentiated small intestinal neuroendocrine tumours (SI‐NETs) are often multifocal, and this has been suggested to impart worse disease‐free survival. Practice guidelines have not been established for World Health Organisation (WHO) grading of multiple primary lesions. read more here.
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Published in 2022 at "Journal of Neuroendocrinology"
DOI: 10.1111/jne.13205
Abstract: We aimed to assess the prognostic impact of tumor‐ and patient‐related parameters in patients with stage I–III small intestinal neuroendocrine tumors (SI‐NETs), who underwent locoregional resective surgery (LRS) with curative intent. We included 229 patients… read more here.
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Published in 2022 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-21-4203
Abstract: Abstract Purpose: The immune tumor microenvironment and the potential therapeutic opportunities for immunotherapy in small intestinal neuroendocrine tumors (siNET) have not been fully defined. Experimental Design: Herein, we studied 40 patients with primary and synchronous… read more here.
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Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221138389
Abstract: Background: Different oncological therapies have been approved for small intestinal neuroendocrine tumors (SI-NETs), but relatively little is known about efficacy and long-term outcome outside of phase III trials. Methods: This retrospective analysis assessed patients with… read more here.
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Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1110396
Abstract: Background: Small intestinal neuroendocrine tumors (SI-NETs) are the most common malignant tumors of the small intestine, with many patients presenting with metastases and their incidence increasing. We aimed to find effective diagnostic biomarkers for patients… read more here.