Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine
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DOI: 10.1007/s11095-019-2701-9
Abstract: Mucins are the principal glycoproteins in mucus and have been implicated in the limitation of intestinal drug absorption; however, the contribution of these molecules to intestinal drug absorption remains unclear. In this study, the relationship… read more here.
Keywords: intestine; intestinal permeation; lipophilic drugs; rat small ... See more keywords
Oleacein Intestinal Permeation and Metabolism in Rats Using an In Situ Perfusion Technique
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DOI: 10.3390/pharmaceutics13050719
Abstract: Oleacein (OLEA) is one of the most important phenolic compounds in extra virgin olive oil in terms of concentration and health-promoting properties, yet there are insufficient data on its absorption and metabolism. Several non-human models… read more here.
Keywords: metabolism rats; intestinal permeation; perfusion; metabolism ... See more keywords