Discrimination between normal and necrotic small intestinal tissue using hyperspectral imaging and unsupervised classification.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300020
Abstract: Objective and automatic clinical discrimination of normal and necrotic sites of small intestinal tissue remains challenging. In this study, hyperspectral imaging (HSI) and unsupervised classification techniques were used to distinguish normal and necrotic sites of… read more here.
Keywords: intestinal tissue; normal necrotic; hyperspectral imaging; discrimination normal ... See more keywords
Superior Adhesion of a Multifunctional Protein‐Based Micropatch to Intestinal Tissue by Harnessing the Hydrophobic Effect
Sign Up to like & getrecommendations! Published in 2022 at "Small Methods"
DOI: 10.1002/smtd.202200153
Abstract: Drug delivery systems comprising drug carriers capable of adhering to intestinal tissue have considerable potential to realize more sophisticated systemic drug delivery and topical drug treatments in the intestinal tract. The development of innovative strategies… read more here.
Keywords: adhesion; carrier; intestinal tissue; drug ... See more keywords
Assessing Phenotypic Heterogeneity in Intestinal Tissue Eosinophils.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1095-4_19
Abstract: Eosinophils are primarily tissue-dwelling leukocytes. Utilization of flow cytometry techniques applied to digested tissues is expanding the scope of organs within which eosinophils are identified at baseline and is providing deeper insights into categorizing phenotypically… read more here.
Keywords: assessing phenotypic; phenotypic heterogeneity; heterogeneity intestinal; tissue ... See more keywords
220.7: Human intestinal tissue-resident memory CD8 T cells comprise two transcriptionally distinct populations
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/01.tp.0000575424.95104.13
Abstract: Michael FitzPatrick, Nicholas Provine, Lucy Garner, Tim Ambrose, Srikanth Reddy, Georgios Vrakas, Peter Friend, Paul Klenerman, Philip Allan Translational Gastroenterology Unit, NDM – Experimental Medicine, University of Oxford; NIHR Biomedical Research Centre, John Radcliffe Hospital,… read more here.
Keywords: 220 human; oxford; tissue resident; resident memory ... See more keywords
Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.01.27.478058
Abstract: Protozoan parasites that infect humans are widespread, and lead to varied clinical manifestations, including life-threatening illnesses in immunocompromised individuals. Animal models have provided insight into innate immunity against parasitic infections, however, species-specific differences and complexity… read more here.
Keywords: microphysiological system; human intestinal; innate immune; intestinal tissue ... See more keywords
Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system.
Sign Up to like & getrecommendations! Published in 2022 at "Science advances"
DOI: 10.1126/sciadv.abm8012
Abstract: Protozoan parasites that infect humans are widespread and lead to varied clinical manifestations, including life-threatening illnesses in immunocompromised individuals. Animal models have provided insight into innate immunity against parasitic infections; however, species-specific differences and complexity… read more here.
Keywords: microphysiological system; system; innate immune; intestinal tissue ... See more keywords
Reduced Incidence of Necrotizing Enterocolitis due to the Anti-Inflammatory Effects of CXCL14 in Intestinal Tissue
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/1322172
Abstract: Bioinformatic analysis indicated that downregulated CXCL14 will occur in the intestinal tissue of patients with necrotizing enterocolitis (NEC). To reveal the relationship between CXCL14 and mucosal immune regulation, we designed and implemented the experiments to… read more here.
Keywords: cxcl14 intestinal; necrotizing enterocolitis; tissue; intestinal tissue ... See more keywords
Abstract 6201: Live biotherapeutic MRx0518 as a modulator of immune responses in intestinal tissue and breast tumor microenvironment
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-6201
Abstract: Introduction: The human gut microbiota plays a role in modulating both intestinal and systemic immunity. Its importance in regulating anti-tumorigenic responses is now being explored, supported by evidence that the functional profile of the gut… read more here.
Keywords: microenvironment; tumor; live biotherapeutic; immune responses ... See more keywords
Visible near-infrared hyperspectral imaging and supervised classification for the detection of small intestinal necrosis tissue in vivo.
Sign Up to like & getrecommendations! Published in 2022 at "Biomedical optics express"
DOI: 10.1364/boe.470202
Abstract: Complete recognition of necrotic areas during small bowel tissue resection remains challenging due to the lack of optimal intraoperative aid identification techniques. This research utilizes hyperspectral imaging techniques to automatically distinguish normal and necrotic areas… read more here.
Keywords: intestinal tissue; supervised classification; hyperspectral imaging; small intestinal ... See more keywords
Isolation of extracellular vesicles from intestinal tissue in a mouse model of intestinal ischemia/reperfusion injury.
Sign Up to like & getrecommendations! Published in 2020 at "BioTechniques"
DOI: 10.2144/btn-2019-0159
Abstract: Extracellular vesicles (EVs) are small membranous particles that contribute to intercellular communications. Separating EVs from tissue is still a technical challenge. Here, we present a rigorous method for extracting EVs from intestinal tissue in a… read more here.
Keywords: extracellular vesicles; tissue mouse; tissue; intestinal ischemia ... See more keywords
Human Intestinal Tissue Explant Exposure to Silver Nanoparticles Reveals Sex Dependent Alterations in Inflammatory Responses and Epithelial Cell Permeability
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22010009
Abstract: Consumer products manufactured with antimicrobial silver nanoparticles (AgNPs) may affect the gastrointestinal (GI) system. The human GI-tract is complex and there are physiological and anatomical differences between human and animal models that limit comparisons between… read more here.
Keywords: silver nanoparticles; sex dependent; tissue; permeability ... See more keywords