Fumonisins B1 exposure triggers intestinal tract injury via activating nuclear xenobiotic receptors and attracting inflammation response.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.115461
Abstract: Fumonisins (FBs) are mycotoxins that are widely distributed in crops and feed, and ingestion of FBs -contaminated crops is harmful to animal health. Furthermore, it is unknown if Fumonisins B1 (FB1) can cause intestinal toxicity.… read more here.
Keywords: fumonisins exposure; inflammation; intestinal toxicity; nuclear xenobiotic ... See more keywords
Genistein-based reactive oxygen species-responsive nanomaterial site-specifically relieves the intestinal toxicity of endocrine-disrupting chemicals.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121478
Abstract: Endocrine-disrupting chemicals (EDCs) can disrupt the gastrointestinal endocrine system and induce oxidative stress, which eventually leads to intestinal toxicity. Genistein (Gen) has a beneficial effect on the physiological functions of the gastrointestinal tract and can… read more here.
Keywords: endocrine; disrupting chemicals; intestinal toxicity; gen ... See more keywords
Circadian variation in intestine toxicity of Mycophenolate mofetil in rats: an experimental and histopathologic study
Sign Up to like & getrecommendations! Published in 2018 at "Biological Rhythm Research"
DOI: 10.1080/09291016.2018.1533732
Abstract: ABSTRACT Mycophenolate mofetil (MMF) as an immunosuppressive agent is used to prevent graft rejection. One of the adverse effects of long time administration of MMF is the gastrointestinal (GI) disorder, which has been associated with… read more here.
Keywords: toxicity; mycophenolate mofetil; intestinal toxicity; study ... See more keywords
Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.587659
Abstract: The gastrointestinal tract is the most common exposure route of xenobiotics, and intestinal toxicity can result in systemic toxicity in most cases. It is important to develop intestinal toxicity assays mimicking the human system; thus,… read more here.
Keywords: toxicity; model; intestinal toxicity; stem ... See more keywords
Preventive Mechanism of Lycopene on Intestinal Toxicity Caused by Cyclophosphamide Chemotherapy in Mice by Regulating TLR4-MyD88/TRIF-TRAF6 Signaling Pathway and Gut-Liver Axis
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14214467
Abstract: Cyclophosphamide (CYC) is the first-line chemotherapy drug for cancer in clinical practice, and its intestinal toxicity seriously affects the treatment effect and prognosis of patients. Lycopene (LP) is the main pigment of ripe tomatoes and… read more here.
Keywords: mice; factor; intestinal toxicity; mechanism ... See more keywords