Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
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DOI: 10.1038/s41598-018-21201-7
Abstract: Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated, and… read more here.
Keywords: human small; intestine chip; small intestine; primary human ... See more keywords
An Intestine-on-a-Chip Model of Plug-and-Play Modularity to Study Inflammatory Processes
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DOI: 10.1177/2472630320924999
Abstract: Development of efficient drugs and therapies for the treatment of inflammatory conditions in the intestine is often hampered by the lack of reliable, robust, and high-throughput in vitro and in vivo models. Current models generally… read more here.
Keywords: intestinal inflammation; chip model; intestine chip; modularity ... See more keywords
Potential of bioprinted intestine-on-chip models in advancing understanding of human coronavirus infections and drug screening
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DOI: 10.36922/ijb.1704
Abstract: Human coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), contribute to both respiratory and gastrointestinal symptoms, necessitating a comprehensive approach to studying viral pathogenesis. In this context, bioprinted intestine-on-chip models offer a cutting-edge technology… read more here.
Keywords: drug screening; intestine chip; chip; chip models ... See more keywords