Acetaminophen absorption and metabolism in an intestine/liver microphysiological system.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.11.010
Abstract: This study describes the characterization of pharmacokinetic (PK) properties of acetaminophen (APAP) in the Two-Organ-Chip platform (2-OC), a two-chamber device able to cultivate 3D tissues under flow. The APAP intestinal absorption and hepatic metabolism were… read more here.
Keywords: absorption; intestine; metabolism; microphysiological system ... See more keywords
Effects of titanium dioxide nanoparticles on the intestine, liver, and kidney of Danio rerio.
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111032
Abstract: Titanium dioxide nanoparticles (Np-TiO2) have become the common component of sunscreen cosmetic products. Np-TiO2 can affect especially aquatic ecosystems health, including aquatic organisms such as fish. It is therefore necessary to acquire a better understanding… read more here.
Keywords: kidney; titanium dioxide; liver; intestine liver ... See more keywords
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas
Sign Up to like & getrecommendations! Published in 2019 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-019-0316-7
Abstract: RNA polymerase III (Pol-III) transcribes tRNAs and other small RNAs essential for protein synthesis and cell growth. Pol-III is deregulated during carcinogenesis; however, its role in vivo has not been studied. To address this issue,… read more here.
Keywords: homeostasis; iii; brf1; pol iii ... See more keywords
Effects of Compound Mycotoxin Detoxifier on Alleviating Aflatoxin B1-Induced Inflammatory Responses in Intestine, Liver and Kidney of Broilers
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14100665
Abstract: In order to alleviate the toxic effects of aflatoxins B1 (AFB1) on inflammatory responses in the intestine, liver, and kidney of broilers, the aflatoxin B1-degrading enzyme, montmorillonite, and compound probiotics were selected and combined to… read more here.
Keywords: inflammatory responses; cmd; group; liver kidney ... See more keywords