Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine‐specific homeobox expression
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22658
Abstract: The aryl hydrocarbon receptor (AHR), a major chemical sensor, is thought to play a role in various biological contexts, including cell cycle regulation and tumorigenesis. However, its regulatory mechanisms remain unclear. We propose herein a… read more here.
Keywords: tumorigenesis; intestine specific; hydrocarbon receptor; aryl hydrocarbon ... See more keywords
Gamma radiative fabrication of semi interpenetrating network film: Optimization, characterization and investigation as colon, intestine specific drug release device
Sign Up to like & getrecommendations! Published in 2018 at "Vacuum"
DOI: 10.1016/j.vacuum.2018.08.005
Abstract: Abstract Presented work was fabrication of colon and intestine specific drugs release device using gamma radiations as initiators. Semi-interpenetrating network (Semi-IPN) film was castoff as drug delivery device to investigate release profile of diethyl carbamazine… read more here.
Keywords: colon intestine; intestine specific; film; release device ... See more keywords
L-Theanine Modulates Intestine-Specific Immunity by Regulating the Differentiation of CD4+ T Cells in Ovalbumin-Sensitized Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c06171
Abstract: Ovalbumin (OVA), a common food protein, can cause deadly allergies with intestine-specific immune reactions. L-Theanine (LTA) shows great potential for regulating intestinal immunity. To investigate the regulatory effect of LTA intervention on intestine-specific immunity, a… read more here.
Keywords: specific immunity; intestine specific; immunity; differentiation ... See more keywords
PO-318 Intestine-specific homeobox gene ISX integrates IL6 signaling, tryptophan catabolism, and immune suppression
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.831
Abstract: Introduction The intestine-specific homeobox transcription factor intestine specific homeobox (ISX) is an IL6-inducible protooncogene implicated in the development of hepatocellular carcinoma, but its mechanistic contributions to this process are undefined. Material and methods In this… read more here.
Keywords: hepatocellular carcinoma; intestine specific; immune suppression; tryptophan ... See more keywords
Abstract 1108: Intestine-specific homeobox recruits p300/CBP-associated factor and bromodomain-containing protein 4 to promote epithelial-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1108
Abstract: The epithelial-mesenchymal transition is an important process in the cancer progression, but its occurrence and the regulatory mechanism are not fully understood. Intestine specific homeobox acted both as a proto-oncogene and upstream regulator of EMT… read more here.
Keywords: bromodomain containing; containing protein; epithelial mesenchymal; specific homeobox ... See more keywords
Intestine‐specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet‐induced barrier dysfunction and glucose intolerance
Sign Up to like & getrecommendations! Published in 2018 at "Physiological Reports"
DOI: 10.14814/phy2.13790
Abstract: Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen. We have earlier demonstrated that consumption of high‐fat high‐cholesterol containing western type‐diet (WD) significantly reduces IAP activity, increases intestinal… read more here.
Keywords: intestine specific; iap; glucose intolerance; mice ... See more keywords
Small Intestine-specific Knockout of CIDEC Improves Obesity and Hepatic Steatosis by Inhibiting Synthesis of Phosphatidic Acid
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.74348
Abstract: The small intestine is main site of exogenous lipid digestion and absorption, and it is important for lipid metabolic homeostasis. Cell death-inducing DNA fragmentation-factor like effector C (CIDEC) is active in lipid metabolism in tissues… read more here.
Keywords: intestine specific; small intestine; cidec; knockout ... See more keywords