Cancer-driving mutations are enriched in genic regions intolerant to germline variation
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DOI: 10.1101/2022.01.07.475416
Abstract: Large reference datasets of protein-coding variation in human populations have allowed us to determine which genes and genic sub-regions are intolerant to germline genetic variation. There is also a growing number of genes implicated in… read more here.
Keywords: germline variation; cancer driving; variation; regions intolerant ... See more keywords