A pioneer study on human 3‐nitropropionic acid intoxication: Contributions from metabolomics
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4259
Abstract: The neurotoxin 3‐nitropropionic acid (3‐NPA) is an inhibitor of succinate dehydrogenase, an enzyme participating both in the citric acid cycle and the mitochondrial respiratory chain. In human intoxications, it produces symptoms such as vomiting and… read more here.
Keywords: intoxication; pioneer study; study human; nitropropionic acid ... See more keywords
[Transdermal intoxication through broken opioid ampules : Accidental intoxication in a paramedic].
Sign Up to like & getrecommendations! Published in 2020 at "Der Anaesthesist"
DOI: 10.1007/s00101-020-00732-7
Abstract: This article presents the case of an accidental transdermal opioid intoxication in a paramedic. During an ambulance flight mission for patient repatriation several ampules containing opioids were broken unnoticed inside the ampule kit in the outside… read more here.
Keywords: broken opioid; transdermal intoxication; intoxication; intoxication paramedic ... See more keywords
Individual prolactin reactivity modulates response of nucleus accumbens to erotic stimuli during acute cannabis intoxication: an fMRI pilot study
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4601-1
Abstract: RationaleSelf-report studies indicate that cannabis could increase sexual desire in some users. We hypothesized that intoxication increases activation of brain areas responsive to visual erotica, which could be useful in the treatment of hypoactive sexual… read more here.
Keywords: response; intoxication; group; study ... See more keywords
Hair analysis does not allow to discriminate between acute and chronic administrations of a drug in young children
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-017-1720-5
Abstract: There are many differences between the hair from children and that of adult subjects, the hair being thinner, more porous with a different growth rate from the usual 1 cm/month observed in adults. In order to… read more here.
Keywords: administration; intoxication; analysis; hair ... See more keywords
Continuous cuprizone intoxication allows active experimental autoimmune encephalomyelitis induction in C57BL/6 mice
Sign Up to like & getrecommendations! Published in 2019 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-019-01786-4
Abstract: Oligodendrocyte degeneration is a hallmark of multiple sclerosis pathology, and protecting oligodendrocytes and myelin is likely to be of clinical relevance. Traditionally, oligodendrocyte and myelin degeneration are viewed as a direct consequence of an inflammatory… read more here.
Keywords: cuprizone; intoxication; autoimmune encephalomyelitis; active experimental ... See more keywords
CYP2B6, ABCB1 and OPRM1 profile in a stillborn affected by chronic methadone intoxication
Sign Up to like & getrecommendations! Published in 2019 at "Forensic Toxicology"
DOI: 10.1007/s11419-019-00478-x
Abstract: The indirect effect of maternal drug exposure on the fetus may include serious consequences such as neonatal abstinence syndrome or, more rarely, intrauterine fetal death (IUFD). Kalin [1] reported the incidence of fetal drug exposure… read more here.
Keywords: mtd exposure; intoxication; case; drug ... See more keywords
On the Efficacy of Cardio-Pulmonary Resuscitation and Epinephrine Following Cyanide- and H2S Intoxication-Induced Cardiac Asystole
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Toxicology"
DOI: 10.1007/s12012-018-9454-2
Abstract: This study was aimed at determining the efficacy of epinephrine, followed by chest compressions, in producing a return of spontaneous circulation (ROSC) during cyanide (CN)- or hydrogen sulfide (H2S)-induced toxic cardiac pulseless electrical activity (PEA)… read more here.
Keywords: epinephrine; intoxication; pea; efficacy ... See more keywords
Faster escalation from first drink to first intoxication as a risk factor for binge and high-intensity drinking among adolescents.
Sign Up to like & getrecommendations! Published in 2019 at "Addictive behaviors"
DOI: 10.1016/j.addbeh.2019.01.003
Abstract: INTRODUCTION Age of first drink is a key risk factor for adolescent high-risk alcohol use. The current study examined whether speed of escalation from first drink to first intoxication is an additional risk factor, and… read more here.
Keywords: intoxication; first intoxication; first drink; high intensity ... See more keywords
IV crystalloid fluid for acute alcoholic intoxication prolongs ED length of stay
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Emergency Medicine"
DOI: 10.1016/j.ajem.2017.12.054
Abstract: Objectives: Acute alcohol intoxication is often treated in emergency departments by intravenous crystalloid fluid (IVF), but it is not clear that this shortens the time to achieving sobriety. The study aim was to investigate the… read more here.
Keywords: without ivf; crystalloid fluid; intoxication; alcoholic intoxication ... See more keywords
Increased risk of peripheral arterial disease in patients with alcohol intoxication: A population-based retrospective cohort study.
Sign Up to like & getrecommendations! Published in 2017 at "Alcohol"
DOI: 10.1016/j.alcohol.2017.06.003
Abstract: Previous studies have reported that light-to-moderate drinkers have a lower risk of peripheral arterial disease (PAD) than abstainers, and that heavy drinking increases the risk of PAD. However, reports of the effects of severe alcohol… read more here.
Keywords: risk; patients alcohol; alcohol intoxication; intoxication ... See more keywords
Acute acetaminophen intoxication induces direct neurotoxicity in rats manifested as astrogliosis and decreased dopaminergic markers in brain areas associated with locomotor regulation.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2019.113662
Abstract: Abstract Acetaminophen (APAP) administration at therapeutic doses is safe, however overdosing produces hepatocellular injury via a multifactorial mechanism(s) that involves generation of reactive oxygen species (ROS), being the most common cause of acute liver failure… read more here.
Keywords: intoxication; astrogliosis; brain areas; acute ... See more keywords